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A facile chemoselective deprotection of the p-methoxybenzyl group
Journal article   Peer reviewed

A facile chemoselective deprotection of the p-methoxybenzyl group

Wensheng Yu, Mei Su, Xiaobang Gao, Zhiqiang Yang and Zhendong Jin
Tetrahedron letters, Vol.41(21), pp.4015-4017
2000
DOI: 10.1016/S0040-4039(00)00574-8

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Abstract

The p-methoxybenzyl (PMB) group can be chemoselectively cleaved at low temperature in the presence of SnCl 4 and thiophenol. This method is especially useful in the cases where oxidative reagents such as DDQ and CAN need to be avoided.
orthoganol deprotection p-methoxybenzyl group thioglycosides

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