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A facile generation of enolates from silyl enol ethers by potassium ethoxide
Journal article   Peer reviewed

A facile generation of enolates from silyl enol ethers by potassium ethoxide

Wensheng Yu and Zhendong Jin
Tetrahedron letters, Vol.42(3), pp.369-372
2001
DOI: 10.1016/S0040-4039(00)01970-5

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Abstract

Cyclic silyl enol ethers were successfully cleaved by EtOK to generate the corresponding enolates. Reactions with EtOK were faster and the corresponding enolates could be trapped by electrophiles and oxidants to give the kinetic products exclusively. Graphic
kinetic enolate oxidation potassium alkyloxide silyl enol ether

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