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A familial/genetic study of plasma serine and glycine concentrations
Journal article   Peer reviewed

A familial/genetic study of plasma serine and glycine concentrations

Eric J Devor and Rafiq Waziri
Biological psychiatry, Vol.34(4), pp.221-225
08/15/1993
DOI: 10.1016/0006-3223(93)90075-O
PMID: 08399818

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Abstract

Plasma serine and glycine concentrations were assayed in a sample of 28 nuclear families (n = 108). Complex segregation analysis of these familial data reveals significant genetic control of concentrations via a single major gene locus. The serine and glycine metabolizing enzyme serine hydroxymethyltransferase (SHMT) is suggested as the most likely candidate for this single major gene locus.
Obstetrics and Gynecology

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