Journal article
A feasibility study of quantitative motor assessments in children using the Q-Motor suite
Journal of Huntington's disease, Vol.8(3), pp.333-338
2019
DOI: 10.3233/JHD-190353
PMCID: PMC7410091
PMID: 31256146
Abstract
Q-Motor is utilized across various clinical trials in adults with Huntington’s Disease (HD) to provide quantitative, reliable assessments of motor abilities. With gene-knockdown therapies entering the clinic, development of preventative therapies for pediatric carriers of the HD mutation seems imminent. It is currently unclear if Q-Motor is useful for tracking changes in motor abilities in pediatric HD patients or at-risk youth, as most assessments have never been administered in children. We demonstrate the feasibility of administering Q-Motor tasks in a sample of children recruited from the community, and we show that Q-Motor is sensitive to age-related changes in motor abilities.
Details
- Title: Subtitle
- A feasibility study of quantitative motor assessments in children using the Q-Motor suite
- Creators
- Ellen van der Plas - University of Iowa Hospital and Clinics, Department of PsychiatryRobin Schubert - George Huntington Institute, Muenster, GermanyRalf Reilmann - George Huntington Institute, Muenster, GermanyPeggy C Nopoulos - University of Iowa Hospital and Clinics, Department of Psychiatry
- Resource Type
- Journal article
- Publication Details
- Journal of Huntington's disease, Vol.8(3), pp.333-338
- DOI
- 10.3233/JHD-190353
- PMID
- 31256146
- PMCID
- PMC7410091
- NLM abbreviation
- J Huntingtons Dis
- ISSN
- 1879-6397
- eISSN
- 1879-6400
- Language
- English
- Date published
- 2019
- Academic Unit
- Neurology; Psychiatry; Stead Family Department of Pediatrics; Iowa Neuroscience Institute
- Record Identifier
- 9984070475402771
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