A gene for autosomal dominant late-onset progressive non-syndromic hearing loss, DFNA10, maps to chromosome 6

Marsha E O'Neill; Jacquie Marietta; Darryl Nishimura; Sigrid Wayne; Guy Van Camp; Lut Van Laer; Clelia Negrini; Edward R Wilcox; Achih Chen; Kunihiro Fukushima; Li Ni; Val C Sheffield; Richard J H Smith

doi:10.1093/hmg/5.6.853

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A gene for autosomal dominant late-onset progressive non-syndromic hearing loss, DFNA10, maps to chromosome 6

Journal article

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A gene for autosomal dominant late-onset progressive non-syndromic hearing loss, DFNA10, maps to chromosome 6

Marsha E O'Neill, Jacquie Marietta, Darryl Nishimura, Sigrid Wayne, Guy Van Camp, Lut Van Laer, Clelia Negrini, Edward R Wilcox, Achih Chen, Kunihiro Fukushima, …

Human molecular genetics, Vol.5(6), pp.853-856

06/1996

DOI: 10.1093/hmg/5.6.853

PMID: 8776603

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Abstract

Late-onset non-syndromic hearing impairment is the most common type of neurological dysfunction in the elderly. It can be either acquired or inherited, although the relative impact of heredity on this type of loss is not known. To date, nine different genes have been localized, but none has been cloned. Using an extended American family in which a gene for autosomal dominant late-onset non-syndromic hearing impairment is segregating, we have identified a new locus, DFNA10, on chromosome 6.

Genes, Dominant

Pedigree

Humans

Middle Aged

Female

Male

Chromosome Mapping

Hearing Loss, Sensorineural - genetics

Chromosomes, Human, Pair 6

Details

Title: Subtitle: A gene for autosomal dominant late-onset progressive non-syndromic hearing loss, DFNA10, maps to chromosome 6
Creators: Marsha E O'Neill - Department of Otolaryngology, University of Iowa, Iowa City 52242, USA
Jacquie Marietta
Darryl Nishimura
Sigrid Wayne
Guy Van Camp
Lut Van Laer
Clelia Negrini
Edward R Wilcox
Achih Chen
Kunihiro Fukushima
Li Ni
Val C Sheffield
Richard J H Smith
Resource Type: Journal article
Publication Details: Human molecular genetics, Vol.5(6), pp.853-856
Publisher: England
DOI: 10.1093/hmg/5.6.853
PMID: 8776603
ISSN: 0964-6906
eISSN: 1460-2083
Language: English
Date published: 06/1996
Academic Unit: Roy J. Carver Department of Biomedical Engineering; Molecular Physiology and Biophysics; Anatomy and Cell Biology; Stead Family Department of Pediatrics; Iowa Neuroscience Institute; Medical Genetics and Genomics; Otolaryngology; Internal Medicine; Ophthalmology and Visual Sciences
Record Identifier: 9984006433802771

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