Journal article
A hemodynamic-driven approach to chronic pulmonary hypertension in congenital diaphragmatic hernia
Journal of perinatology
02/23/2026
DOI: 10.1038/s41372-026-02582-4
PMID: 41731046
Abstract
Despite ample research in acute pulmonary hypertension in neonates with congenital diaphragmatic hernia (CDH) leading to improved survival, there is a paucity of literature on the physiology of chronic pulmonary hypertension in this population. Serial hemodynamic assessments and physiology-centric care have been shown to be safe and effective in the acute transitional and peri-operative care of these neonates and will likely be informative in the discussion of chronic pulmonary hypertension as well. Herein, we discuss the epidemiology, contributors, and proposed physiology-based phenotypes of chronic pulmonary hypertension in neonates with CDH. Further investigation is needed to contribute to our understanding and treatment of chronic pulmonary hypertension in this complex, heterogeneous population.
Details
- Title: Subtitle
- A hemodynamic-driven approach to chronic pulmonary hypertension in congenital diaphragmatic hernia
- Creators
- Carly E Byrd - Johns Hopkins UniversityJohn T Wren Jr - University of Iowa, NeonatologySuneetha Desiraju - Johns Hopkins UniversityPatrick J McNamara - University of Iowa Hospitals and Clinics
- Resource Type
- Journal article
- Publication Details
- Journal of perinatology
- DOI
- 10.1038/s41372-026-02582-4
- PMID
- 41731046
- NLM abbreviation
- J Perinatol
- ISSN
- 1476-5543
- eISSN
- 1476-5543
- Publisher
- Springer Nature
- Language
- English
- Electronic publication date
- 02/23/2026
- Academic Unit
- Stead Family Department of Pediatrics; Neonatology
- Record Identifier
- 9985139275802771
Metrics
1 Record Views