Journal article
A lag-phase in the reduction of flavin dependent thymidylate synthase (FDTS) revealed a mechanistic missing link
Chemical communications (Cambridge, England), Vol.2006(16), pp.1781-1783
2006
DOI: 10.1039/b517881a
PMID: 16609803
Abstract
An unexpected substrate-dependent lag-phase, found in the single turnover reduction of FDTS bound flavin, sheds light on the molecular mechanism of this alternative thymidylate synthase.
Details
- Title: Subtitle
- A lag-phase in the reduction of flavin dependent thymidylate synthase (FDTS) revealed a mechanistic missing link
- Creators
- Aaron MasonNitish AgrawalM. Todd WashingtonScott A LesleyAmnon Kohen
- Resource Type
- Journal article
- Publication Details
- Chemical communications (Cambridge, England), Vol.2006(16), pp.1781-1783
- DOI
- 10.1039/b517881a
- PMID
- 16609803
- NLM abbreviation
- Chem Commun (Camb)
- ISSN
- 1359-7345
- eISSN
- 1364-548X
- Publisher
- Royal Society of Chemistry
- Language
- English
- Date published
- 2006
- Academic Unit
- Radiation Oncology; Biochemistry and Molecular Biology; Chemistry
- Record Identifier
- 9984025291902771
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