A latent class analysis of prolonged mechanical ventilation patients at a long-term acute care hospital: Subtype differences in clinical outcomes

Heather Dunn; Laurie Quinn; Susan Corbridge; Mary Kapella; Kamal Eldeirawi; Alana Steffen; Eileen Collins

doi:10.1016/j.hrtlng.2019.01.001

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A latent class analysis of prolonged mechanical ventilation patients at a long-term acute care hospital: Subtype differences in clinical outcomes

Journal article

Peer reviewed

A latent class analysis of prolonged mechanical ventilation patients at a long-term acute care hospital: Subtype differences in clinical outcomes

Heather Dunn, Laurie Quinn, Susan Corbridge, Mary Kapella, Kamal Eldeirawi, Alana Steffen and Eileen Collins

Heart & lung, Vol.48(3), pp.215-221

05/01/2019

DOI: 10.1016/j.hrtlng.2019.01.001

PMCID: PMC6874913

PMID: 30655004

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Abstract

Patients on prolonged mechanical ventilation (PMV) at Long-Term Acute Care Hospital's (LTACHs) are clinically heterogeneous making it difficult to manage care and predict clinical outcomes. Identify and describe subgroups of patients on PMV at LTACHs and examine for group differences. Latent class analysis was completed on data obtained during medical record review at Midwestern LTACH. A three-class solution was identified. Class 1 contained young, obese patients with low clinical and co-morbid burden; Class 2 contained the oldest patients with low clinical burden but multiple co-morbid conditions; Class 3 contained patients with multiple clinical and co-morbid burdens. There were no differences in LTACH length of stay [F(2,246) = 2.243, p = 0.108] or number of ventilator days [F(2,246) = 0.641, p = 0.528]. Class 3 patients were less likely to wean from mechanical ventilation [χ2(2, N = 249) = 25.48, p < 0.001] and more likely to die [χ2(2, N = 249) = 23.68, p < 0.001]. Patient subgroups can be described that predict clinical outcomes. Class 3 patients are at higher risk for poor clinical outcomes when compared to patients in Class 1 or Class 2.

Latent class analysis

Long-term acute care hospital

Mortality

Prolonged mechanical ventilation

Subgroup

Ventilator weaning

Details

Title: Subtitle: A latent class analysis of prolonged mechanical ventilation patients at a long-term acute care hospital: Subtype differences in clinical outcomes
Creators: Heather Dunn - University of Iowa
Laurie Quinn - University of Illinois at Chicago
Susan Corbridge - University of Illinois at Chicago
Mary Kapella - University of Illinois at Chicago
Kamal Eldeirawi - University of Illinois at Chicago
Alana Steffen - University of Illinois at Chicago
Eileen Collins - University of Illinois at Chicago
Resource Type: Journal article
Publication Details: Heart & lung, Vol.48(3), pp.215-221
Publisher: Elsevier Inc
DOI: 10.1016/j.hrtlng.2019.01.001
PMID: 30655004
PMCID: PMC6874913
ISSN: 0147-9563
eISSN: 1527-3288
Grant note: University of Illinois at Chicago (http://dx.doi.org/10.13039/100010443)
Language: English
Date published: 05/01/2019
Academic Unit: Nursing
Record Identifier: 9984370746802771

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