Journal article
A longitudinal examination of parent-reported emotional-behavioral functioning of children with mild to moderate chronic kidney disease
Pediatric nephrology (Berlin, West), Vol.35(7), pp.1287-1295
07/2020
DOI: 10.1007/s00467-020-04511-9
PMCID: PMC8210580
PMID: 32157444
Abstract
Children with mild to moderate chronic kidney disease (CKD) are at increased risk for deficits in neurocognition. Less is known about how CKD affects emotional-behavioral functioning in this population.
Parent ratings of emotional-behavioral functioning at baseline and over time were examined for 845 children with mild to moderate CKD using the Behavior Assessment System for Children, Second Edition Parent Rating Scales (BASC-2 PRS). Associations with demographic and disease-related predictors were also examined.
Children with mild to moderate CKD had parent-reported emotional-behavioral functioning largely within normal limits, at baseline and over time. The proportion with T-scores at least 1 SD above the mean was 24% for Internalizing Problems and 28% for Attention Problems. A greater proportion of participants scored lower than expected (worse) on scales measuring adaptive skills (25%). Persistent hypertension predicted attention problems (β = 1.59, 95% CI = 0.24 to 2.94, p < 0.02) and suggested worse behavioral symptoms (β = 1.36, 95% CI = - 0.01 to 2.73, p = 0.05). Participants with proteinuria at baseline, but not at follow-up, had fewer attention problems than participants whose proteinuria had not resolved (β = - 3.48, CI = - 6.79 to - 0.17, p < 0.04). Glomerular diagnosis was related to fewer (β = - 2.68, 95% CI = - 4.93 to - 0.42, p < 0.02) internalizing problems.
Although children with CKD generally have average emotional-behavioral parent ratings, a notable percentage of the population may be at risk for problems with attention and adaptive behavior. Providers working with this population should facilitate psychosocial referrals when indicated.
Details
- Title: Subtitle
- A longitudinal examination of parent-reported emotional-behavioral functioning of children with mild to moderate chronic kidney disease
- Creators
- Rebecca J Johnson - Division of Developmental and Behavioral Health, Children's Mercy Kansas City, University of Missouri - Kansas City School of Medicine, 2401 Gillham Road, Kansas City, MO, 64108, USA. rejohnson@cmh.eduArlene C Gerson - Johns Hopkins Medical Institute, Baltimore, MD, USALyndsay A Harshman - University of Iowa Stead Family Children's Hospital, Iowa City, IA, USAMatthew B Matheson - Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USAShlomo Shinnar - Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USAMarc B Lande - University of Rochester Medical Center, Rochester, NY, USAAmy Kogon - Children's Hospital of Philadelphia, Philadelphia, PA, USADebbie S Gipson - University of Michigan School of Medicine, Ann Arbor, MI, USABradley A Warady - Division of Nephrology, Children's Mercy Kansas City, University of Missouri - Kansas City School of Medicine, 2401 Gillham Road, Kansas City, MO, 64108, USASusan L Furth - Children's Hospital of Philadelphia, Philadelphia, PA, USAStephen R Hooper - School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
- Resource Type
- Journal article
- Publication Details
- Pediatric nephrology (Berlin, West), Vol.35(7), pp.1287-1295
- DOI
- 10.1007/s00467-020-04511-9
- PMID
- 32157444
- PMCID
- PMC8210580
- NLM abbreviation
- Pediatr Nephrol
- ISSN
- 0931-041X
- eISSN
- 1432-198X
- Publisher
- Germany
- Grant note
- U01-DK-66143, U01-DK-66174, U24-DK-082194, U24-DK-66116 / Eunice Kennedy Shriver National Institute of Child Health and Human Development U01-DK-66143, U01-DK-66174, U24-DK-082194, U24-DK-66116 / NIDDK NIH HHS K23 DK110443 / NIDDK NIH HHS U01 DK066143 / NIDDK NIH HHS U01-DK-66143, U01-DK-66174, U24-DK-082194, U24-DK-66116 / NHLBI NIH HHS
- Language
- English
- Date published
- 07/2020
- Academic Unit
- Nephrology, Dialysis and Transplantation; Stead Family Department of Pediatrics; Iowa Neuroscience Institute; Radiation Oncology
- Record Identifier
- 9984070610502771
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