Journal article
A maternal mRNA localized to the animal pole of Xenopus eggs encodes a subunit of mitochondrial ATPase
Proceedings of the National Academy of Sciences - PNAS, Vol.84(9), pp.2798-2802
1987
DOI: 10.1073/pnas.84.9.2798
PMID: 2953029
Abstract
We have previously isolated several cDNA clones of mRNAs that have the unusual property of being localized to either the animal pole or the vegetal pole of frog eggs. To gain insight into the function of these maternal mRNAs we have determined their DNA sequence and deduced the sequence of the proteins they encode. Here we report that An2, an mRNA localized to the animal pole of Xenopus oocytes and eggs, codes for the alpha chain of mitochondrial ATPase. Furthermore, we compare the intracellular localization of the An2 mRNA and mitochondria in oocytes and eggs and find that they do not have the same degree of localization. In the light of these results we discuss possible reasons for the maternal localization of the An2 mRNA.
Details
- Title: Subtitle
- A maternal mRNA localized to the animal pole of Xenopus eggs encodes a subunit of mitochondrial ATPase
- Creators
- D. L WEEKS - Harvard univ., dep. biochemistry & molecular biology, Cambridge MA 02138, United StatesD. A MELTON - Harvard univ., dep. biochemistry & molecular biology, Cambridge MA 02138, United States
- Resource Type
- Journal article
- Publication Details
- Proceedings of the National Academy of Sciences - PNAS, Vol.84(9), pp.2798-2802
- DOI
- 10.1073/pnas.84.9.2798
- PMID
- 2953029
- NLM abbreviation
- Proc Natl Acad Sci U S A
- ISSN
- 0027-8424
- eISSN
- 1091-6490
- Publisher
- National Academy of Sciences of the United States of America; Washington, DC
- Language
- English
- Date published
- 1987
- Academic Unit
- Stead Family Department of Pediatrics; Biochemistry and Molecular Biology
- Record Identifier
- 9984025267102771
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