Journal article
A multi-centre evaluation of oral cancer in Southern and Western Nigeria: an African oral pathology research consortium initiative
The Pan African medical journal, Vol.28, pp.64-64
2017
DOI: 10.11604/pamj.2017.28.64.13089
PMCID: PMC5873219
PMID: 29599879
Abstract
Oral cancer is a leading cause of cancer deaths among African populations. Lack of standard cancer registries and under-reporting has inaccurately depicted its magnitude in Nigeria. Development of multi-centre collaborative oral pathology networks such as the African Oral Pathology Research Consortium (AOPRC) facilitates skill and expertise exchange and fosters a robust and systematic investigation of oral diseases across Africa.
In this descriptive cross-sectional study, we have leveraged the auspices of the AOPRC to examine the burden of oral cancer in Nigeria, using a multi-centre approach. Data from 4 major tertiary health institutions in Western and Southern Nigeria was generated using a standardized data extraction format and analysed using the SPSS data analysis software (version 20.0; SPSS Inc. Chicago, IL).
Of the 162 cases examined across the 4 centres, we observed that oral squamous cell carcinomas (OSCC) occurred mostly in the 6
and 7
decades of life and maxillary were more frequent than mandibular OSCC lesions. Regional variations were observed both for location, age group and gender distribution. Significant regional differences was found between poorly, moderately and well differentiated OSCC (p value = 0.0071).
A multi-centre collaborative oral pathology research approach is an effective way to achieve better insight into the patterns and distribution of various oral diseases in men of African descent. The wider outlook for AOPRC is to employ similar approaches to drive intensive oral pathology research targeted at addressing the current morbidity and mortality of various oral diseases across Africa.
Details
- Title: Subtitle
- A multi-centre evaluation of oral cancer in Southern and Western Nigeria: an African oral pathology research consortium initiative
- Creators
- Olufemi Gbenga Omitola - Department of Oral Pathology and Biology, University of Port Harcourt, Port Harcourt, NigeriaOlujide Oladele Soyele - Department of Oral Maxillo-Facial Surgery and Oral Pathology, Obafemi Awolowo University, Ile-Ife, NigeriaOpeyemi Sigbeku - Department of Oral Pathology, College of Medicine, University of Ibadan, Ibadan, NigeriaDickson Okoh - Department of Oral Pathology, School of Dentistry, University of Calabar, NigeriaAbdulwarith Olaitan Akinshipo - Department of Oral and Maxillofacial Pathology & Biology, College of Medicine, University of Lagos, Lagos, NigeriaAzeez Butali - Department of Oral Pathology, Radiology and Medicine, University of Iowa, Iowa City, IA, USAHenry Ademola Adeola - Division of Dermatology, Department of Medicine, Faculty of Health Sciences and Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa
- Resource Type
- Journal article
- Publication Details
- The Pan African medical journal, Vol.28, pp.64-64
- DOI
- 10.11604/pamj.2017.28.64.13089
- PMID
- 29599879
- PMCID
- PMC5873219
- NLM abbreviation
- Pan Afr Med J
- ISSN
- 1937-8688
- eISSN
- 1937-8688
- Publisher
- Uganda
- Language
- English
- Date published
- 2017
- Academic Unit
- Oral Pathology, Radiology and Medicine; Stead Family Department of Pediatrics; Craniofacial Anomalies Research Center; Dental Research
- Record Identifier
- 9984066098902771
Metrics
26 Record Views