Journal article
A multicenter investigation examining timing of penile prosthesis infection management and responsible organisms
International journal of impotence research, Vol.36(3), pp.214-217
05/01/2024
DOI: 10.1038/s41443-022-00659-0
PMID: 36564583
Abstract
The purpose of this investigation was to examine the timing of penile prosthesis infection management by different responsible organisms. A retrospective cohort study was performed of patients who underwent penile prosthesis salvage or explant procedures due to a suspected infection between 2001 and 2018. The cohort consisted of 216 patients from 33 different facilities and six countries. The most common primary organisms responsible for device infections included, Gram-positives (31.5%), no growth cultures (30.6%), Gram-negatives (22.2%), fungal (11.6%), and anaerobic organisms (4.2%). Overall, median time to infection was 1.8 (interquartile range [IQR]: 1.0-3.0) months for all patients. Median time to infection management was similar between responsible organisms: 1.0 (IQR: 1.0-2.3) months for Gram-negatives and 2 months for Gram-positives (IQR: 1.0-1.4), fungal (IQR: 1.0-5.0), anaerobes (IQR: 1.0-2.5), and no growth cultures (IQR: 1.0-3.0, p = 0.56). Median time to infection management was significantly shorter among patients who received aminoglycoside/vancomycin prophylaxis (1.5 months, IQR: 1.0-2.5, p < 0.01) compared to other antibiotic groups. Median time to infection management was significantly longer for patients managed with a three-piece inflatable implant salvage procedure (2.8 months, IQR: 1.0-5.0, p = 0.02) compared to other salvage procedures. Conventional wisdom surrounding early versus late penile prosthesis infections should largely be abandoned. More than half of penile prosthesis infections are surgically managed within 2 months of initial device placement.
Details
- Title: Subtitle
- A multicenter investigation examining timing of penile prosthesis infection management and responsible organisms
- Creators
- Michael E Rezaee - Johns Hopkins HospitalAmanda R Swanton - Boston Medical CenterMartin S Gross - Dartmouth–Hitchcock Medical CenterRicardo M Munarriz - Boston Medical Center
- Resource Type
- Journal article
- Publication Details
- International journal of impotence research, Vol.36(3), pp.214-217
- DOI
- 10.1038/s41443-022-00659-0
- PMID
- 36564583
- ISSN
- 0955-9930
- eISSN
- 1476-5489
- Language
- English
- Date published
- 05/01/2024
- Academic Unit
- Urology
- Record Identifier
- 9984701648402771
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