A national study on the use of opioid analgesics in dentistry

Patrícia Azevedo Lino; Woosung Sohn; Astha Singhal; Maria Auxiliadora Parreiras Martins; Maria Elisa de Souza E Silva; Mauro Henrique Nogueira Guimarães de Abreu

doi:10.1590/1807-3107bor-2019.vol33.0076

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A national study on the use of opioid analgesics in dentistry

Journal article

Open access

Peer reviewed

A national study on the use of opioid analgesics in dentistry

Patrícia Azevedo Lino, Woosung Sohn, Astha Singhal, Maria Auxiliadora Parreiras Martins, Maria Elisa de Souza E Silva and Mauro Henrique Nogueira Guimarães de Abreu

Brazilian oral research, Vol.33, pp.e076-e076

08/15/2019

DOI: 10.1590/1807-3107bor-2019.vol33.0076

PMID: 31432927

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https://doi.org/10.1590/1807-3107bor-2019.vol33.0076View

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Abstract

The aim of this study was to assess the frequency of opioid analgesics prescribed by Brazilian dentists, potential regional differences and their association with socioeconomic and health-related factors. Data for all opioid prescriptions by dentists was obtained from the 2012 database of the National Controlled Substances Management System, regulated by the Brazilian Health Surveillance Agency. The number of defined daily doses (DDD) and DDDs per 1,000 inhabitants per day for each Brazilian state were calculated as the primary outcomes. DDDs were compared by regions and Brazilian states. Spearman's rho correlation coefficient was used to determine the influence of the states' characteristics, such as the Human Development Index; poverty; education; number of dentists per 100,000 inhabitants; visit to the dentist; dental care plan; good or very good oral health; number of pharmaceutical establishments per 100,000/inhabitants; and ability to get all prescribed medications. Data analysis was performed using IBM SPSS Statistics 25.0. A total of 141,161 prescriptions for opioids analgesics by 36,929 dentists were recorded, corresponding to 658,855 doses of opioids dispensed in 2012. The most commonly dispensed opioids were codeine associated with paracetamol (83.2%; n = 117,493). The national DDDs per 1,000 inhabitants per day was 0.0093 (range: 0.0002-0.0216). DDD per 1,000 inhabitants per day was positively associated to visits to dentists (rs = 0.630; P < 0.001) and inversely associated to poverty (rs = -0.624; p = 0.001). There are significant differences in opioid prescriptions in dentistry among the Brazilian states. These differences may be associated with non-clinical factors.

Acetaminophen - therapeutic use

Analgesics, Opioid - therapeutic use

Brazil

Codeine - therapeutic use

Cross-Sectional Studies

Dental Care - statistics & numerical data

Drug Prescriptions - statistics & numerical data

Drug Utilization - statistics & numerical data

Humans

Pharmacies - statistics & numerical data

Practice Patterns, Dentists' - statistics & numerical data

Reference Values

Socioeconomic Factors

Statistics, Nonparametric

Tramadol - therapeutic use

Details

Title: Subtitle: A national study on the use of opioid analgesics in dentistry
Creators: Patrícia Azevedo Lino - Universidade Federal de Minas Gerais
Woosung Sohn - The University of Sidney, School of Medicine, Sidney, New South Wales, Australia.
Astha Singhal - Boston University
Maria Auxiliadora Parreiras Martins - Universidade Federal de Minas Gerais
Maria Elisa de Souza E Silva - Universidade Federal de Minas Gerais
Mauro Henrique Nogueira Guimarães de Abreu - Universidade Federal de Minas Gerais
Resource Type: Journal article
Publication Details: Brazilian oral research, Vol.33, pp.e076-e076
DOI: 10.1590/1807-3107bor-2019.vol33.0076
PMID: 31432927
NLM abbreviation: Braz Oral Res
ISSN: 1806-8324
eISSN: 1807-3107
Language: English
Date published: 08/15/2019
Academic Unit: Public Policy Center (Archive)
Record Identifier: 9984283851802771

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