A pathogenic germline BRCA2 variant in a patient with hypopharyngeal squamous cell carcinoma

Tatiana Correa; Douglas E. Laux; Henry T. Hoffman

doi:10.1002/ccr3.3548

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A pathogenic germline BRCA2 variant in a patient with hypopharyngeal squamous cell carcinoma

Journal article

Open access

Peer reviewed

A pathogenic germline BRCA2 variant in a patient with hypopharyngeal squamous cell carcinoma

Tatiana Correa, Douglas E. Laux and Henry T. Hoffman

Clinical case reports, Vol.9(1), pp.429-432

01/01/2021

DOI: 10.1002/ccr3.3548

PMCID: PMC7813105

PMID: 33489192

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Abstract

Pathogenic germline BRCA2 variants may be associated with an increased risk of hypopharyngeal squamous cell carcinoma that is more responsive to chemoradiation and chemotherapeutics targeting defective double-strand DNA repair.

General & Internal Medicine

Life Sciences & Biomedicine

Medicine, General & Internal

Science & Technology

Details

Title: Subtitle: A pathogenic germline BRCA2 variant in a patient with hypopharyngeal squamous cell carcinoma
Creators: Tatiana Correa - University of Iowa
Douglas E. Laux - University of Iowa
Henry T. Hoffman - University of Iowa
Resource Type: Journal article
Publication Details: Clinical case reports, Vol.9(1), pp.429-432
DOI: 10.1002/ccr3.3548
PMID: 33489192
PMCID: PMC7813105
NLM abbreviation: Clin Case Rep
ISSN: 2050-0904
eISSN: 2050-0904
Publisher: Wiley
Number of pages: 4
Grant note: P30 CA086862 / NCI NIH HHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI)
Language: English
Date published: 01/01/2021
Academic Unit: Hematology, Oncology, and Blood & Marrow Transplantation; Radiation Oncology; Otolaryngology; Internal Medicine
Record Identifier: 9984312247202771

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