A potential relationship between diffuse musculoskeletal pain and hypogonadism

Jaclyn K Anderson; Rebecca Tuetken; Valerie Hoffman

doi:10.1136/bcr.08.2009.2152

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A potential relationship between diffuse musculoskeletal pain and hypogonadism

Journal article

Open access

Peer reviewed

A potential relationship between diffuse musculoskeletal pain and hypogonadism

Jaclyn K Anderson, Rebecca Tuetken and Valerie Hoffman

BMJ case reports, Vol.2010(feb02 1), pp.bcr0820092152-bcr0820092152

2010

DOI: 10.1136/bcr.08.2009.2152

PMCID: PMC3027404

PMID: 22242044

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Abstract

Some men presenting with diffuse musculoskeletal pain have testosterone values below the normal range for their age. While scant evidence suggests that functional status in such men may improve with testosterone replacement therapy, there are currently no published studies evaluating a potential correlation between diffuse musculoskeletal pain and male hypogonadism. In a cohort of 45 hypogonadal men with diffuse musculoskeletal pain we found a negative correlation between the duration of pain in years and baseline total testosterone values. Although advancing age would theoretically predispose individuals to lower testosterone concentrations, age was not independently associated with baseline testosterone values, nor were any other variables we examined. At this time generalised screening of gonadal function for such men is not indicated. A prospective study would more clearly evaluate a potential relationship between diffuse musculoskeletal pain and testosterone values in men and might determine if testosterone replacement leads to any measurable improvement.

Details

Title: Subtitle: A potential relationship between diffuse musculoskeletal pain and hypogonadism
Creators: Jaclyn K Anderson - University of Nebraska Medical Center, Department of Internal Medicine, Section of Rheumatology and Immunology, Nebraska Medical Center, Omaha, Nebraska, -, USA
Rebecca Tuetken - University of Iowa Hospitals and Clinics, Department of Internal Medicine, University of Iowa Carver College of Medicine, Hawkins Drive, Iowa City, Iowa, , USA
Valerie Hoffman - University of Iowa Hospitals and Clinics, Department of Internal Medicine, University of Iowa Carver College of Medicine, Hawkins Drive, Iowa City, Iowa, , USA
Resource Type: Journal article
Publication Details: BMJ case reports, Vol.2010(feb02 1), pp.bcr0820092152-bcr0820092152
DOI: 10.1136/bcr.08.2009.2152
PMID: 22242044
PMCID: PMC3027404
NLM abbreviation: BMJ Case Rep
ISSN: 1757-790X
eISSN: 1757-790X
Language: English
Date published: 2010
Academic Unit: Epidemiology; Immunology; Internal Medicine
Record Identifier: 9984094727502771

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