Journal article
A practical approach to caring for atopic dermatitis in children
Current opinion in pediatrics, Vol.35(6), pp.686-691
12/01/2023
DOI: 10.1097/MOP.0000000000001293
PMID: 37779485
Abstract
Purpose of review
Atopic dermatitis is a chronic, systemic disease with primary cutaneous clinical manifestations and is commonly attributed to an exaggerated Th2 inflammatory response. Recent research regarding risk factors, prevention, clinical features, and management of atopic dermatitis will be reviewed.
Recent findings
In the last decade, advances have been made in identifying the factors that either confer increased risk for or protection from atopic dermatitis and associated atopy. Progress has also been made in the clinical management of this disease. Promising biomarkers and therapeutically informative characteristics of this disease have been identified in young children with and without the presence of eczema, but much has yet to be elucidated. Progress has also been made in clarifying the advantages and disadvantages of respective medical managements, including but not limited to topical corticosteroids, topical calcineurin inhibitors, phototherapy, systemic immunosuppressants, and targeted immunotherapy. Given that medical management may show variable efficacy in a child, an optimized skin care regimen is of utmost importance as well.
Summary
Atopic dermatitis is a challenging, chronic systemic disease that incurs significant morbidity in affected children. Although management options have been somewhat disappointing in years past, promising results have been observed in recent advances in targeted immunotherapy. Copyright (C) 2023 Wolters Kluwer Health, Inc. All rights reserved.
Details
- Title: Subtitle
- A practical approach to caring for atopic dermatitis in children
- Creators
- Diana K. Bayer - University of Iowa Stead Family Children’s Hospital
- Resource Type
- Journal article
- Publication Details
- Current opinion in pediatrics, Vol.35(6), pp.686-691
- Publisher
- Lippincott Williams & Wilkins
- DOI
- 10.1097/MOP.0000000000001293
- PMID
- 37779485
- ISSN
- 1040-8703
- eISSN
- 1531-698X
- Number of pages
- 6
- Language
- English
- Date published
- 12/01/2023
- Academic Unit
- Stead Family Department of Pediatrics; Rheumatology, Allergy, and Immunology; Internal Medicine
- Record Identifier
- 9984695836502771
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