A randomized controlled trial of interleukin-1 receptor antagonist in a rabbit model of ascending infection in pregnancy

Robert S. McDuffie Jr.; Jill K Davies; Kimberly K. Leslie; Scott Lee; Michael P Sherman; Ronald S Gibbs

doi:10.1155/S1064744901000382

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A randomized controlled trial of interleukin-1 receptor antagonist in a rabbit model of ascending infection in pregnancy

Journal article

Open access

Peer reviewed

A randomized controlled trial of interleukin-1 receptor antagonist in a rabbit model of ascending infection in pregnancy

Robert S. McDuffie Jr., Jill K Davies, Kimberly K. Leslie, Scott Lee, Michael P Sherman and Ronald S Gibbs

Infectious diseases in obstetrics and gynecology, Vol.9(4), pp.233-237

2001

DOI: 10.1155/S1064744901000382

PMCID: PMC1784656

PMID: 11916181

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https://doi.org/10.1242/dev.02739View

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Abstract

Objective: To determinewhether treatment with interleukin-1 receptor antagonist (IL1-ra) would affect amniotic fluid concentrations of tumor necrosis factor alpha (TNF-α) and prostaglandins or clinical or microbiological outcomes in a model of ascending bacterial infection in pregnancy.

Pregnancy

Receptors

Obstetrics and Gynecology

Amniotic Fluid

Animals

Body Temperature

Dinoprostone

Disease Models

Animal

Escherichia coli

Escherichia coli Infections

Female

Interleukin 1 Receptor Antagonist Protein

Pregnancy Complications

Infectious

Rabbits

Random Allocation

Interleukin-1

Sialoglycoproteins

Tumor Necrosis Factor-alpha

Details

Title: Subtitle: A randomized controlled trial of interleukin-1 receptor antagonist in a rabbit model of ascending infection in pregnancy
Creators: Robert S. McDuffie Jr.
Jill K Davies
Kimberly K. Leslie - University of Colorado Denver
Scott Lee
Michael P Sherman
Ronald S Gibbs
Resource Type: Journal article
Publication Details: Infectious diseases in obstetrics and gynecology, Vol.9(4), pp.233-237
DOI: 10.1155/S1064744901000382
PMID: 11916181
PMCID: PMC1784656
ISSN: 1064-7449
Copyright: Copyright © 2001 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Language: English
Date published: 2001
Academic Unit: Obstetrics and Gynecology
Record Identifier: 9983557415502771

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