Journal article
A unique approach to the synthesis of 2,3,4,5-substituted polybrominated biphenyls: quantitation in FireMaster FF-1 and FireMaster BP-6
Journal of agricultural and food chemistry, Vol.37(4), pp.1160-1164
07/01/1989
DOI: 10.1021/jf00088a075
Abstract
A scheme is presented that allows the efficient synthesis of four anilines (3,5-di-, 3,4,5-tri-, 2,3,4,5-tetra-, and 2,3,4,5,6-pentabromoanilines) as well as 1,2,3,4-tetrabromobenzene from a single starting material. All of these products are useful precursors in the synthesis of polybrominated biphenyls (PBBs), The aryl-aryl coupling of bromoanilines with 1,2,3,4-tetrabromobenzene provides a versatile approach to the synthesis of 2,3,4,5-tetrasubstituted PBBs for the first time. The synthesis and characterization of nine such PBBs are reported here. Interestingly, aside from the desired coupling product, the 2,2ʹ,3,3ʹ,4,4ʹ,5,5ʹ-octabromobiphenyl was a byproduct of each coupling reaction, ranging from less than 2% to 63% of the polybrominated biphenyl products. Capillary gas chromatographic quantitation of the nine synthetic PBBs in fireMaster FF-1 and fireMaster BP-6 is presented. © 1989, American Chemical Society. All rights reserved.
Details
- Title: Subtitle
- A unique approach to the synthesis of 2,3,4,5-substituted polybrominated biphenyls: quantitation in FireMaster FF-1 and FireMaster BP-6
- Creators
- Gerhard A KubiczakFranz OeschJuergen T BorlakogluHorst KunzLarry W Robertson
- Resource Type
- Journal article
- Publication Details
- Journal of agricultural and food chemistry, Vol.37(4), pp.1160-1164
- Publisher
- American Chemical Society
- DOI
- 10.1021/jf00088a075
- ISSN
- 0021-8561
- eISSN
- 1520-5118
- Language
- English
- Date published
- 07/01/1989
- Academic Unit
- Occupational and Environmental Health
- Record Identifier
- 9984363611202771
Metrics
7 Record Views