Journal article
AAEM minimonograph #37: Facial and limb myokymia
Muscle & nerve, Vol.14(11), pp.1043-1049
11/1991
DOI: 10.1002/mus.880141102
PMID: 1745276
Abstract
Myokymia is a clinical phenomenon associated with characteristic electromyographic activity referred to as myokymic discharges. These are spontaneously generated bursts of individual motor unit potentials with each burst recurring rhythmically or semirhythmically, usually several times per second. It involves facial muscles more commonly than those of the extremities, and is most often seen in association with Guillain‐Barré syndrome, multiple sclerosis, radiation plexopathy, pontine tumors, and timber rattlesnake envenomation. An alteration in the biochemical microenvironment of axon membranes at one of the various sites along the motor axon is the likely basis for the altered membrane excitability that underlies the myokymic discharges in most cases. The similarity of these discharges to those seen with hypocalcemic tetany, and the ability to manipulate myokymic discharges by altering serum‐ionized Ca++, suggests that decrease in the ionized Ca++ in the microenvironment of the axon may play an important role.
Details
- Title: Subtitle
- AAEM minimonograph #37: Facial and limb myokymia
- Creators
- Ludwig Gutmann
- Resource Type
- Journal article
- Publication Details
- Muscle & nerve, Vol.14(11), pp.1043-1049
- Publisher
- Wiley Subscription Services, Inc., A Wiley Company; Hoboken
- DOI
- 10.1002/mus.880141102
- PMID
- 1745276
- ISSN
- 0148-639X
- eISSN
- 1097-4598
- Number of pages
- 7
- Language
- English
- Date published
- 11/1991
- Academic Unit
- Neurology
- Record Identifier
- 9984020758202771
Metrics
23 Record Views