Journal article
AIE Luminogens as Versatile Bioprobes
Current analytical chemistry, Vol.17(3), pp.302-316
03/11/2021
DOI: 10.2174/1573411016666200110153737
Abstract
Background: Luminogens that feature aggregation induced emission (AIE) are typically non-emissive in solution but become highly luminescent upon aggregation in poor solvents or solid state. Discussion: Unlike conventional fluorophores that exhibit aggregation-caused quenching (ACQ), utilization of AIE luminogens as bioprobes has featured superior photostability, low background signal, large Stokes’ shifts, high sensitivity and turn-on luminescent response. Conclusion: The versatility of AIE-based luminogens as bioprobes has been demonstrated through various applications in cell organelle imaging, ion sensing and sensitive detection of biomacromolecules. Examples of AIE-based luminogens and their applications as luminescent sensors for biosensing and optical imaging are discussed herein.
Details
- Title: Subtitle
- AIE Luminogens as Versatile Bioprobes
- Creators
- Moustafa T Gabr - Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, United StatesF. Christopher Pigge - Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, United States
- Resource Type
- Journal article
- Publication Details
- Current analytical chemistry, Vol.17(3), pp.302-316
- DOI
- 10.2174/1573411016666200110153737
- ISSN
- 1573-4110
- eISSN
- 1875-6727
- Language
- English
- Date published
- 03/11/2021
- Academic Unit
- Radiology; Chemistry
- Record Identifier
- 9984216719702771
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