Journal article
ALTERATIONS IN CEREBROSPINAL FLUID SODIUM AND OSMOLALITY IN RATS DURING ONE-KIDNEY, ONE-WRAP RENAL HYPERTENSION
Clinical and experimental pharmacology & physiology, Vol.11(5), pp.545-549
Received 6 January 1984; revision received I2 April 1984
10/1984
DOI: 10.1111/j.1440-1681.1984.tb00865.x
PMID: 6525769
Abstract
1. Measurements of plasma and cerebrospinal fluid (CSF) sodium and osmolality were made throughout the course of one‐kidney, one‐wrap Grollman renal hypertension. 2. Although the plasma sodium and osmolality did not rise after 28 days, CSF sodium and osmolality was increased significantly at 3 days postwrap. 3. As a result, the CSF to plasma ratio for both sodium and osmolality was significantly elevated during the initial postwrap period. 4. These observations suggest that an increase in CSF sodium may provide an initiating stimulus for an elevated arterial pressure in one‐kidney, one‐wrap renal hypertension. Copyright © 1984, Wiley Blackwell. All rights reserved
Details
- Title: Subtitle
- ALTERATIONS IN CEREBROSPINAL FLUID SODIUM AND OSMOLALITY IN RATS DURING ONE-KIDNEY, ONE-WRAP RENAL HYPERTENSION
- Creators
- J. R Haywood - Departments of Pharmacology and Psychology, The Iowa Cardiovascular Center and The Veterans' Administration Medical Center, University of Iowa, Iowa City, Iowa, USAJ Buggy - Departments of Pharmacology and Psychology, The Iowa Cardiovascular Center and The Veterans' Administration Medical Center, University of Iowa, Iowa City, Iowa, USAG. D Fink - Departments of Pharmacology and Psychology, The Iowa Cardiovascular Center and The Veterans' Administration Medical Center, University of Iowa, Iowa City, Iowa, USAG. F DiBona - Departments of Pharmacology and Psychology, The Iowa Cardiovascular Center and The Veterans' Administration Medical Center, University of Iowa, Iowa City, Iowa, USAA. K Johnson - Departments of Pharmacology and Psychology, The Iowa Cardiovascular Center and The Veterans' Administration Medical Center, University of Iowa, Iowa City, Iowa, USAM. J Brody - Departments of Pharmacology and Psychology, The Iowa Cardiovascular Center and The Veterans' Administration Medical Center, University of Iowa, Iowa City, Iowa, USA
- Resource Type
- Journal article
- Publication Details
- Clinical and experimental pharmacology & physiology, Vol.11(5), pp.545-549
- Edition
- Received 6 January 1984; revision received I2 April 1984
- Publisher
- Blackwell Publishing Ltd
- DOI
- 10.1111/j.1440-1681.1984.tb00865.x
- PMID
- 6525769
- ISSN
- 0305-1870
- eISSN
- 1440-1681
- Number of pages
- 5
- Language
- English
- Date published
- 10/1984
- Academic Unit
- Psychological and Brain Sciences; Neuroscience and Pharmacology; Health and Human Physiology; Internal Medicine
- Record Identifier
- 9984213263702771
Metrics
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