Journal article
ALTERED PLASMA LIPID AND LIPOPROTEIN LEVELS ASSOCIATED WITH ORAL CONTRACEPTIVE AND ŒSTROGEN USE: Report from the Medications Working Group of the Lipid Research Clinics Program
The Lancet (British edition), Vol.314(8134), pp.111-115
1979
DOI: 10.1016/S0140-6736(79)90001-1
Abstract
In a study of women attending ten North American Lipid Research Clinics plasma total cholesterol, triglyceride, low density (L.D.L.), very low density (V.L.D.L.), and high density (H.D.L.) lipoprotein levels in those taking oral contraceptives (o.c.) and in those taking œstrogens for menopausal symptoms were compared with those in women not taking gonadal hormones, after adjustment for age, educational attainment, and body-mass index. o.c. and œstrogen users were leaner than non-users. Compared with controls, o.c. users showed increased cholesterol, triglyceride, and L.D.L.-cholesterol and V.L.D.L.-cholesterol levels, but H.D.L.-cholesterol levels were similar. Cholesterol, triglyceride, and H.D.L.-cholesterol and V.L.D.L.-cholesterol levels were positively associated with the quantity of the œstrogen component of the o.c. preparations. Compared with non-users, menopausal œstrogen users had slightly lower cholesterol and triglyceride levels, significant de- creases in L.D.L.-cholesterol and V.L.D.L.-cholesterol, and a significant increase in H.D.L.-cholesterol.
Details
- Title: Subtitle
- ALTERED PLASMA LIPID AND LIPOPROTEIN LEVELS ASSOCIATED WITH ORAL CONTRACEPTIVE AND ŒSTROGEN USE: Report from the Medications Working Group of the Lipid Research Clinics Program
- Creators
- RobertB Wallace - University of Iowa College of Medicine, Iowa City, United StatesJoanne Hoover - University of WashingtonElizabeth Barrett-Connor - University of California San DiegoBasilM Rifkind - National Heart Lung and Blood InstituteDonaldB Hunninghake - University of MinnesotaArden Mackenthun - Oklahoma Medical Research FoundationGerardo Heiss - University of North Carolina at Chapel Hill
- Resource Type
- Journal article
- Publication Details
- The Lancet (British edition), Vol.314(8134), pp.111-115
- DOI
- 10.1016/S0140-6736(79)90001-1
- ISSN
- 0140-6736
- eISSN
- 1474-547X
- Publisher
- Elsevier Ltd
- Language
- English
- Date published
- 1979
- Academic Unit
- Epidemiology; Injury Prevention Research Center; Internal Medicine
- Record Identifier
- 9984363614702771
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