Journal article
AN AUGMENTED KELLER-SEGEL MODEL FOR E. COLI CHEMOTAXIS IN FAST-VARYING ENVIRONMENTS
Communications in mathematical sciences, Vol.14(3), pp.883-891
01/01/2016
DOI: 10.4310/CMS.2016.v14.n3.a12
Abstract
This is a continuous study on E. coli chemotaxis under the framework of pathway-based mean-field theory (PBMFT) proposed in [G. Si, M. Tang, and X. Yang, 12, 907-926, 2014], following the physical studies in [G. Si, T. Wu, Q. Quyang, and Y. Tu, 109, 048101, 2012]. In this paper, we derive an augmented Keller-Segel system with macroscopic intercellular signaling pathway dynamics. It can explain the experimental observation of phase-shift between the maxima of ligand concentration and density of E. coli in fast-varying environments at the population level. This is a necessary complement to the original PBMFT where the phase-shift can only be modeled by moment systems. Formal analysis are given for the system in the cases of fast and slow adaption rates. Numerical simulations show the quantitative agreement of the augmented Keller-Segel model with the individual-based E. coli chemotaxis simulator.
Details
- Title: Subtitle
- AN AUGMENTED KELLER-SEGEL MODEL FOR E. COLI CHEMOTAXIS IN FAST-VARYING ENVIRONMENTS
- Creators
- Tong Li - University of IowaMin Tang - Shanghai Jiao Tong UniversityXu Yang - University of California, Santa Barbara
- Resource Type
- Journal article
- Publication Details
- Communications in mathematical sciences, Vol.14(3), pp.883-891
- Publisher
- INT PRESS BOSTON, INC
- DOI
- 10.4310/CMS.2016.v14.n3.a12
- ISSN
- 1539-6746
- eISSN
- 1945-0796
- Number of pages
- 9
- Grant note
- DMS-1418936; DMS-1107291 / NSF 13PJ140700 / Shanghai Pujiang Program 11301336; 91330203 / NSFC 12ZR1445400 / NSF of Shanghai Hellman Family Foundation Faculty Fellowship, UC Santa Barbara
- Language
- English
- Date published
- 01/01/2016
- Academic Unit
- Mathematics
- Record Identifier
- 9984240869402771
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