Abnormal fatty acid breath tests in cancer patients, with nutritional correlation

W E Delaney; E Nickoloff; D S Ettinger; H M Drew; D J Szeluga; R K Stuart

doi:10.1002/1097-0142(19820815)50:4<727::aid-cncr2820500417>3.0.co;2-q

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Abnormal fatty acid breath tests in cancer patients, with nutritional correlation

Journal article

Peer reviewed

Abnormal fatty acid breath tests in cancer patients, with nutritional correlation

W E Delaney, E Nickoloff, D S Ettinger, H M Drew, D J Szeluga and R K Stuart

Cancer, Vol.50(4), pp.727-731

08/15/1982

DOI: 10.1002/1097-0142(19820815)50:4<727::aid-cncr2820500417>3.0.co;2-q

PMID: 7093907

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Abstract

In a group of cancer patients selected to exclude common causes of abnormal lipid absorption, we have examined this function using a breath test. Abnormal breath tests of fatty acid absorption (FABT) are found in most cancer patients, as has been previously claimed. These tests are abnormal in both quality (delayed peak in nine of ten patients, and quantity (reduced maximum peak in five of ten patients) of fatty acid absorption. In many patients abnormal FABT is not due to chemotherapy. Our preliminary results indicate no definite malabsorption mechanism but more stringent tests of absorption need to be applied. Malnutrition is common in cancer patients, even in those with little or no weight loss, and some of the malnutrition may be related to abnormal lipid absorption or to other disturbed aspects of lipid metabolism.

Lipid Metabolism

Lung Neoplasms - drug therapy

Body Weight

Humans

Lung Neoplasms - metabolism

Middle Aged

Breath Tests

Fatty Acids - analysis

Male

Malabsorption Syndromes - metabolism

Breast Neoplasms - drug therapy

Intestinal Absorption

Breast Neoplasms - metabolism

Nutrition Disorders - etiology

Pilot Projects

Malabsorption Syndromes - etiology

Nutrition Disorders - metabolism

Diet

Adult

Female

Aged

Fatty Acids - pharmacology

Details

Title: Subtitle: Abnormal fatty acid breath tests in cancer patients, with nutritional correlation
Creators: W E Delaney
E Nickoloff
D S Ettinger
H M Drew
D J Szeluga
R K Stuart
Resource Type: Journal article
Publication Details: Cancer, Vol.50(4), pp.727-731
DOI: 10.1002/1097-0142(19820815)50:4<727::aid-cncr2820500417>3.0.co;2-q
PMID: 7093907
NLM abbreviation: Cancer
ISSN: 0008-543X
eISSN: 1097-0142
Publisher: United States
Grant note: NIH-NCI-CA-17970 / NCI NIH HHS NIH-MCI-CA-06973 / NCI NIH HHS
Language: English
Date published: 08/15/1982
Academic Unit: Anesthesia; Urology
Record Identifier: 9984006413702771

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