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Abnormal multifocal electroretinogram (mfERG) in ethambutol toxicity
Journal article   Peer reviewed

Abnormal multifocal electroretinogram (mfERG) in ethambutol toxicity

Randy H Kardon, Mary C Morrisey and Andrew G Lee
Seminars in ophthalmology, Vol.21(4), pp.215-222
10/2006
DOI: 10.1080/08820530600987454
PMID: 17182409

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Abstract

To report the abnormal multifocal electroretinogram (mfERG) findings in two cases of presumed ethambutol toxicity. Retrospective observational case series. Two patients with ethambutol toxicity and visual loss. Multifocal electroretinography. Waveform measurements on multifocal electroretinography. Two patients with bilateral visual loss due to ethambutol toxicity underwent mfERG testing that disclosed both diffuse and central field loss compatible with retinal dysfunction as a contributing mechanism to the visual field loss. Ethambutol toxicity affects not only the optic nerve but probably other retinal elements based upon abnormal mfERG findings.
Electroretinography Retina - drug effects Antitubercular Agents - adverse effects Retinal Diseases - diagnosis Humans Middle Aged Retina - physiopathology Retinal Diseases - chemically induced Visual Acuity Ethambutol - adverse effects Vision Disorders - diagnosis Vision Disorders - physiopathology Visual Fields Vision Disorders - chemically induced Aged, 80 and over Female Visual Field Tests Retinal Diseases - physiopathology

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