Journal article
Acanthamoeba Keratitis: A Single-Institution Series of Four Cases With Literature Review
Curēus (Palo Alto, CA), Vol.14(1), pp.e21112-e21112
01/11/2022
DOI: 10.7759/cureus.21112
PMCID: PMC8830394
PMID: 35165570
Abstract
Acanthamoeba
species are free-living protozoa found pervasively in water and soil, which can cause infections of the central nervous system, skin, and eye. Amoebic keratitis (AK) is a vision-threatening, often chronic infection that is associated with the use of soft contact lenses due to corneal microtrauma and improper cleaning and storage. Although AK infections are rare, they cause significant morbidity including vision loss due to the diagnostic and therapeutic challenges they pose.
The clinical course is determined by the organism’s inherent pathogenicity, delay of diagnosis, and the paucity of data on effective therapeutic regimens. The case series and review of literature that follows examine current latest best practices in AK diagnosis including in vivo confocal microscopy (IVCM) and therapeutic interventions including miltefosine.
Details
- Title: Subtitle
- Acanthamoeba Keratitis: A Single-Institution Series of Four Cases With Literature Review
- Creators
- Clarissa Smith - University of Kansas Medical CenterNida Ashraf - University of Kansas Medical CenterMegan Haghnegahdar - University of Kansas Medical CenterKenneth Goins - University of Kansas Medical CenterJessica R Newman - University of Kansas Medical Center
- Resource Type
- Journal article
- Publication Details
- Curēus (Palo Alto, CA), Vol.14(1), pp.e21112-e21112
- DOI
- 10.7759/cureus.21112
- PMID
- 35165570
- PMCID
- PMC8830394
- NLM abbreviation
- Cureus
- ISSN
- 2168-8184
- eISSN
- 2168-8184
- Publisher
- Cureus
- Language
- English
- Date published
- 01/11/2022
- Academic Unit
- Ophthalmology and Visual Sciences
- Record Identifier
- 9984808213302771
Metrics
6 Record Views