Acceptable rates of treatment failure in osteomyelitis involving the diabetic foot: a survey of infectious diseases consultants

Eli N Perencevich; Keith S Kaye; Larry J Strausbaugh; David N Fisman; Anthony D Harris; Infectious Diseases Society of America Emerging Infections Network

doi:10.1086/381029

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Acceptable rates of treatment failure in osteomyelitis involving the diabetic foot: a survey of infectious diseases consultants

Journal article

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Acceptable rates of treatment failure in osteomyelitis involving the diabetic foot: a survey of infectious diseases consultants

Eli N Perencevich, Keith S Kaye, Larry J Strausbaugh, David N Fisman, Anthony D Harris and Infectious Diseases Society of America Emerging Infections Network

Clinical infectious diseases, Vol.38(4), pp.476-482

02/15/2004

DOI: 10.1086/381029

PMID: 14765338

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Abstract

Shortening the duration of antibiotic therapy is an attractive strategy for delaying the emergence of antimicrobial resistance. The paucity of data about optimal treatment durations hinders adoption of this approach. This study used contingent valuation analysis to identify failure rates for treatment of diabetic foot osteomyelitis acceptable to infectious diseases consultants (IDCs). The Infectious Diseases Society of America's Emerging Infections Network (EIN) provided members with the case scenario and 1 of 10 failure rates; members were asked, assuming delivery of standard therapy, if they would accept or reject the given failure rate. The relationship between specific failure rates and the willingness of IDCs to accept them was analyzed. The median acceptable failure rate for EIN members was 18.1%; 75% of IDCs found a failure rate of 7.8% to be acceptable, and 25% found a rate of 28.4% to be acceptable. The methodology used in this study may prove useful in delineating acceptable treatment failure thresholds, an initial step in shortening durations of antimicrobial therapy.

Diabetic Foot - complications

Humans

Diabetic Foot - drug therapy

Data Collection

Osteomyelitis - complications

Osteomyelitis - drug therapy

Osteomyelitis - mortality

Consultants

Pilot Projects

Communicable Diseases - drug therapy

Diabetic Foot - mortality

Treatment Failure

Adult

Surveys and Questionnaires

Communicable Diseases - complications

Communicable Diseases - mortality

Details

Title: Subtitle: Acceptable rates of treatment failure in osteomyelitis involving the diabetic foot: a survey of infectious diseases consultants
Creators: Eli N Perencevich - VA Maryland Healthcare System, Dept. of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA. eperence@epi.umaryland.edu
Keith S Kaye
Larry J Strausbaugh
David N Fisman
Anthony D Harris
Infectious Diseases Society of America Emerging Infections Network
Resource Type: Journal article
Publication Details: Clinical infectious diseases, Vol.38(4), pp.476-482
DOI: 10.1086/381029
PMID: 14765338
NLM abbreviation: Clin Infect Dis
ISSN: 1058-4838
eISSN: 1537-6591
Publisher: United States
Grant note: U50/CCU112346 / ODCDC CDC HHS K23 AI01752-01A1 / NIAID NIH HHS
Language: English
Date published: 02/15/2004
Academic Unit: Epidemiology; Internal Medicine
Record Identifier: 9984001182302771

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Acceptable rates of treatment failure in osteomyelitis involving the diabetic foot: a survey of infectious diseases consultants

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