Journal article
Accuracy and Reproducibility of Real-Time Three-Dimensional Echocardiography for Assessment of Right Ventricular Volumes and Ejection Fraction in Children
Journal of the American Society of Echocardiography, Vol.21(1), pp.84-89
2008
DOI: 10.1016/j.echo.2007.05.009
PMID: 17628408
Abstract
Measurement of right ventricular (RV) volumes and ejection fraction (EF) by two-dimensional echocardiography has limited accuracy and reproducibility because of the complex RV geometry.
This study sought to validate real-time three-dimensional echocardiography (RT3DE) using a disk summation method for assessment of RV volumes and RVEF in children by comparing it with magnetic resonance imaging (MRI) measurements.
A total of 20 children (mean age 10.6 ± 2.8 years) were studied. Transthoracic RT3DE was performed using a RT3DE system to acquire full-volume RT3DE data sets from apical windows and data were processed offline using a software package. RV end-systolic volume and end-diastolic volume (EDV) were measured using a disk summation method by manually tracing the endocardial borders. RVEF was calculated as: RVEF = (EDV − end-systolic volume)/EDV × 100%. All participants also underwent MRI studies for comparison of RV indexes.
Of the 20 children, 3 were excluded because of poor or incomplete RV images (two RT3DE and one MRI study). For the remaining 17 children, good correlation and agreement between RT3DE and MRI were found (RVEDV:
r = 0.98,
P < .001, mean difference = −7.0 ± 9.0 mL,
P < .01; RV end-systolic volume:
r = 0.96,
P < .001, mean difference = −3.2 ± 7.1 mL,
P > .05; RVEF:
r = 0.89,
P < .001, mean difference = −0.3 ± 7.1%,
P > .05). The intraobserver and the interobserver variabilities ranged from −1.1% to 5.8%.
Measurement of RV volumes and EF by RT3DE is feasible, accurate, and reproducible in children compared with MRI measurements.
Details
- Title: Subtitle
- Accuracy and Reproducibility of Real-Time Three-Dimensional Echocardiography for Assessment of Right Ventricular Volumes and Ejection Fraction in Children
- Creators
- Xiuzhang Lu - Baylor College of Medicine and Texas Children’s Hospital, Houston, TexasVyacheslav Nadvoretskiy - Baylor College of Medicine and Texas Children’s Hospital, Houston, TexasLiping Bu - University of Iowa, Iowa City, IowaAlan Stolpen - University of Iowa, Iowa City, IowaNancy Ayres - Baylor College of Medicine and Texas Children’s Hospital, Houston, TexasRicardo H Pignatelli - Baylor College of Medicine and Texas Children’s Hospital, Houston, TexasJohn P Kovalchin - Baylor College of Medicine and Texas Children’s Hospital, Houston, TexasMichelle Grenier - Baylor College of Medicine and Texas Children’s Hospital, Houston, TexasBerthold Klas - TomTec Imaging Systems, Munich, GermanyShuping Ge - Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas
- Resource Type
- Journal article
- Publication Details
- Journal of the American Society of Echocardiography, Vol.21(1), pp.84-89
- Publisher
- Mosby, Inc
- DOI
- 10.1016/j.echo.2007.05.009
- PMID
- 17628408
- ISSN
- 0894-7317
- eISSN
- 1097-6795
- Language
- English
- Date published
- 2008
- Academic Unit
- Radiology; Internal Medicine
- Record Identifier
- 9984051986102771
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