Journal article
Accuracy of the HPV status site‐specific factor 10 (SSF‐10) variable for patients with oropharyngeal cancers in the Iowa Cancer Registry, 2010‐2014
Head & neck, Vol.40(10), pp.2199-2209
10/2018
DOI: 10.1002/hed.25314
PMCID: PMC6197903
PMID: 29934978
Abstract
Background
Surveillance, Epidemiology, and End Results Cancer Registries (SEER) began collecting human papillomavirus (HPV) status for upper aerodigestive tract cancers in 2010. However, classification of p16‐testing was not included in the Collaborative Stage coding guidelines, potentially leading to inconsistent coding.
Methods
The HPV values for Iowa patients with oropharyngeal cancers (n = 824) were recoded based on modified guidelines that included p16 test results, and compared with the original guidelines.
Results
Forty percent of patients were recoded to a different value, and the HPV testing rate increased from 45% to 55%; 56% received p16‐testing only. Of those originally coded as HPV‐type 16 (n = 187), 89% were recoded to HPV‐not otherwise specified (NOS). When comparing high‐level positive/negative/not done categories, original coding captured 81% of patients with HPV‐positive cancers.
Conclusion
p16 was the most common HPV test but was inconsistently coded as HPV‐testing. p16‐positivity was also erroneously equated with HPV‐type 16. Adding a separate p16 variable would improve consistency and accuracy of HPV coding.
Details
- Title: Subtitle
- Accuracy of the HPV status site‐specific factor 10 (SSF‐10) variable for patients with oropharyngeal cancers in the Iowa Cancer Registry, 2010‐2014
- Creators
- Amanda R Kahl - University of Iowa College of Public Health & the Iowa Cancer RegistryMary E Charlton - University of Iowa College of Public Health & the Iowa Cancer RegistryNitin A Pagedar - University of IowaSteven M Sperry - University of IowaBobbi Matt - University of Iowa College of Public Health & the Iowa Cancer RegistryCharles Platz - University of Iowa College of Public Health & the Iowa Cancer RegistryCharles F Lynch - University of Iowa College of Public Health & the Iowa Cancer Registry
- Resource Type
- Journal article
- Publication Details
- Head & neck, Vol.40(10), pp.2199-2209
- DOI
- 10.1002/hed.25314
- PMID
- 29934978
- PMCID
- PMC6197903
- NLM abbreviation
- Head Neck
- ISSN
- 1043-3074
- eISSN
- 1097-0347
- Number of pages
- 11
- Grant note
- National Institutes of Health (NIH)/National Cancer Institute (NCI) (HHSN261201300020I)
- Language
- English
- Date published
- 10/2018
- Academic Unit
- Health Management and Policy; Epidemiology; Pathology; Otolaryngology
- Record Identifier
- 9983995173302771
Metrics
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