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Accurate measurement of intrathoracic airways
Journal article   Peer reviewed

Accurate measurement of intrathoracic airways

J. M Reinhardt, N. D D'SOUZA and E. A Hoffman
IEEE transactions on medical imaging, Vol.16(6), pp.820-827
1997
DOI: 10.1109/42.650878
PMID: 9533582

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Abstract

Airway geometry measurements can provide information regarding pulmonary physiology and pathophysiology. There has been considerable interest in measuring intrathoracic airways in two-dimensional (2-D) slices from volumetric X-ray computed tomography (CT). Such measurements can be used to evaluate and track the progression of diseases affecting the airways. A popular airway measurement method uses the "half-max" criteria, in which the gray level at the airway wall is estimated to be halfway between the minimum and maximum gray levels along a ray crossing the edge. However, because the scanning process introduces blurring, the half-max approach may not be applicable across all airway sizes. We propose a new measurement method based on a model of the scanning process. In our approach, we examine the gray-level profile of a ray crossing the airway wall and use a maximum-likelihood method to estimate the airway inner and outer radius. Using CT scans of a physical phantom, we present results showing that the new approach is more accurate than the half-max method at estimating wall location for thin-walled airways.
Respiratory System Biological and medical sciences Investigative techniques, diagnostic techniques (general aspects) Medical sciences Radiodiagnosis. Nmr imagery. Nmr spectrometry

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