Journal article
Acidogenicity and acid tolerance of Streptococcus oralis and Streptococcus mitis isolated from plaque of healthy and incipient caries teeth
Journal of Oral Microbiology, Vol.8(1), 32940
01/01/2016
DOI: 10.3402/jom.v8.32940
PMCID: PMC5084378
PMID: 27790973
Abstract
Non-mutans low pH oral streptococci are postulated to contribute to caries etiology. This study was undertaken to investigate whether the acidogenicity and acid tolerance of clinical strains of Streptococcus oralis and Streptococcus mitis correlate with health or early-stage enamel caries. S. oralis and S. mitis were isolated from plaque samples taken from the occlusal surfaces of second molars sampled at two different visits 4 years apart. All sites were sound at Visit 1; subjects were segregated into one of three groups based on the status of the site at Visit 2 and caries elsewhere in the dentition. Strains of S. oralis and S. mitis were evaluated for acidogenicity and acid tolerance, and the results correlated with the clinical status of the sites from which they were isolated. Mutans streptococci (MS) isolated from the plaque samples were also quantified, and the presence or absence of growth on pH 5.5 media or on media selective for bifidobacteria was recorded. No significant positive correlations were found between the acidogenicity properties of the S. oralis and S. mitis clones and caries at either visit. Similar results were obtained for acid tolerance of S. oralis clones but were inconclusive for S. mitis clones. A statistically significant positive correlation between MS levels and caries (or future caries) was evident at both visits, but there were no statistical correlations with the growth on pH 5.5 media or media selective for bifidobacteria. The low pH potential likely varies considerably among oral streptococcal species and is least likely to be found among strains of S. mitis. Accordingly, the concept and constitution of 'low pH streptococci' may need to be re-evaluated.
Details
- Title: Subtitle
- Acidogenicity and acid tolerance of Streptococcus oralis and Streptococcus mitis isolated from plaque of healthy and incipient caries teeth
- Creators
- Jeffrey A Banas - Iowa Institute for Oral Health Research, University of Iowa College of DentistryMin Zhu - Iowa Institute for Oral Health Research, University of Iowa College of DentistryDeborah V Dawson - Iowa Institute for Oral Health Research, University of Iowa College of DentistryDerek R Blanchette - Iowa Institute for Oral Health Research, University of Iowa College of DentistryDavid R Drake - Iowa Institute for Oral Health Research, University of Iowa College of DentistryHongjie Gu - Iowa Institute for Oral Health Research, University of Iowa College of DentistryRyan Frost - Iowa Institute for Oral Health Research, University of Iowa College of DentistryGrant McCaulley - Iowa Institute for Oral Health Research, University of Iowa College of DentistrySteven M Levy - Department of Preventive and Community DentistryUniversity of Iowa College of Dentistry Iowa City
- Resource Type
- Journal article
- Publication Details
- Journal of Oral Microbiology, Vol.8(1), 32940
- DOI
- 10.3402/jom.v8.32940
- PMID
- 27790973
- PMCID
- PMC5084378
- NLM abbreviation
- J Oral Microbiol
- ISSN
- 2000-2297
- eISSN
- 2000-2297
- Publisher
- Taylor & Francis
- Language
- English
- Date published
- 01/01/2016
- Academic Unit
- Preventive and Community Dentistry; Endodontics; Epidemiology; Biostatistics; Pediatric Dentistry; Dental Research
- Record Identifier
- 9983917687002771
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