Journal article
Acoustofluidic methods in cell analysis
TrAC, Trends in analytical chemistry (Regular ed.), Vol.117, pp.280-290
08/2019
DOI: 10.1016/j.trac.2019.06.034
PMID: 32461706
Abstract
Cellular analysis is a central concept for both biology and medicine. Over the past two decades, acoustofluidic technologies, which marry acoustic waves with microfluidics, have significantly contributed to the development of innovative approaches for cellular analysis. Acoustofluidic technologies enable precise manipulations of cells and the fluids that confine them, and these capabilities have been utilized in many cell analysis applications. In this review article, we examine various applications where acoustofluidic methods have been implemented, including cell imaging, cell mechanotyping, circulating tumor cell phenotyping, sample preparation in clinics, and investigation of cell-cell interactions and cell-environment responses. We also provide our perspectives on the technological advantages, limitations, and potential future directions for this innovative field of methods.
Details
- Title: Subtitle
- Acoustofluidic methods in cell analysis
- Creators
- Yuliang Xie - Pennsylvania State UniversityHunter Bachman - Duke UniversityTony Jun Huang - Duke University
- Resource Type
- Journal article
- Publication Details
- TrAC, Trends in analytical chemistry (Regular ed.), Vol.117, pp.280-290
- DOI
- 10.1016/j.trac.2019.06.034
- PMID
- 32461706
- NLM abbreviation
- Trends Analyt Chem
- ISSN
- 0165-9936
- eISSN
- 1879-3142
- Grant note
- DOI: 10.13039/100000001, name: National Science Foundation; DOI: 10.13039/100000002, name: National Institutes of Health
- Language
- English
- Date published
- 08/2019
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering
- Record Identifier
- 9984197122502771
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