Journal article
Action plan for an international imaging framework for implementation of global low-dose CT screening for lung cancer
European journal of cancer (1990), Vol.220, 115323
05/02/2025
DOI: 10.1016/j.ejca.2025.115323
PMID: 40022837
Abstract
Reduction in lung cancer mortality is achievable through low dose computed tomography (LDCT) screening in high-risk individuals. Many countries are progressing from local LDCT screening studies to national screening programs. Implementation of effective large-scale screening programs is complex and requires a multi-disciplinary approach. A recent overview of the technical aspects of implementing high quality LDCT for screening resulted from the inaugural international expert meeting of the Alliance for Global Implementation of Lung and Cardiac Early Disease Detection and Treatment (AGILE). This covers the most important aspects of the CT imaging process: standardisation in CT image acquisition and interpretation, CT protocol management, technology developments and minimal requirements, integration of lung cancer biomarkers, and the role of AI in CT lung nodule detection, segmentation, and classification, and related data security issues.
•Implementation of lung cancer screening using CT imaging is expanding globally•CT screening is evolving to include the early detection of other thoracic diseases•Standardisation of the CT-imaging process is essential•Novel technologies and AI will support global screening implementation•Amultidisciplinary approach is necessary to ensure through, trustworthy validation
Details
- Title: Subtitle
- Action plan for an international imaging framework for implementation of global low-dose CT screening for lung cancer
- Creators
- Harriet L. Lancaster - University Medical Center GroningenAnna N.H. Walstra - Institute for Diagnostic Accuracy, Groningen, NLKyle Myers - Texas A&M UniversityRicardo S. Avila - Accumetra, Clifton Park, New York, USAJan Willem C. Gratama - Gelre HospitalsMarjolein A. Heuvelmans - University Medical Center GroningenSean B. Fain - University of IowaDavid A. Clunie - PixelMed Publishing, Bangor, Pennsylvania, USAElla A. Kazerooni - Michigan MedicineMaryellen L. Giger - University of ChicagoAnthony P. Reeves - Cornell UniversityJens Vogel-Claussen - Medizinische Hochschule HannoverHarry de Koning - Icahn School of Medicine at Mount SinaiRowena Yip - Icahn School of Medicine at Mount SinaiLuis M. Seijo - Clinica Universidad de NavarraJohn K. Field - University of LiverpoolJames L. Mulshine - Rush University Medical CenterMario Silva - University of Massachusetts Chan Medical SchoolDavid F. Yankelevitz - Icahn School of Medicine at Mount SinaiMatthijs Oudkerk - University of GroningenClaudia I. Henschke - Icahn School of Medicine at Mount Sinai
- Resource Type
- Journal article
- Publication Details
- European journal of cancer (1990), Vol.220, 115323
- Publisher
- Elsevier Ltd
- DOI
- 10.1016/j.ejca.2025.115323
- PMID
- 40022837
- ISSN
- 0959-8049
- eISSN
- 1879-0852
- Language
- English
- Electronic publication date
- 02/22/2025
- Date published
- 05/02/2025
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Radiology; Electrical and Computer Engineering; Health and Human Physiology
- Record Identifier
- 9984795377702771
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