Journal article
Activation of supraoptic magnocellular neurons by gamma2-melanocyte stimulating hormone (γ2-MSH)
Brain research, Vol.480(1-2), pp.388-392
1989
DOI: 10.1016/0006-8993(89)90213-8
Abstract
The effects of intracarotid infusions of the peptide gamma2-melanocyte stimulating hormone (γ2-MSH) on electrophysiologically and immunohistochemically identified supraoptic nucleus (SON) units were investigated Over a wide dose range this agent always excited SON units, while control infusions of vehicle had no effect. Because neural responses invariably preceded blood pressure elevation, it appears that γ2-MSH excitation of the magnocellular system was due to a direct effect on the central nervous system and was not a result of systemic cardiovascular responses. These results suggest a forebrain γ2-MSH sensitive site in the activation of SON magnocellular neurons.
Details
- Title: Subtitle
- Activation of supraoptic magnocellular neurons by gamma2-melanocyte stimulating hormone (γ2-MSH)
- Creators
- L. D Mitchell - Univ. Iowa, dep. psychology, Iowa City IA 52242, United StatesM. F Callahan - Univ. Iowa, dep. psychology, Iowa City IA 52242, United StatesL. D Wilkin - Univ. Iowa, dep. psychology, Iowa City IA 52242, United StatesK. A Gruber - Univ. Iowa, dep. psychology, Iowa City IA 52242, United StatesA. K Johnson - Univ. Iowa, dep. psychology, Iowa City IA 52242, United States
- Resource Type
- Journal article
- Publication Details
- Brain research, Vol.480(1-2), pp.388-392
- Publisher
- Elsevier
- DOI
- 10.1016/0006-8993(89)90213-8
- ISSN
- 0006-8993
- eISSN
- 1872-6240
- Language
- English
- Date published
- 1989
- Academic Unit
- Neuroscience and Pharmacology; Health and Human Physiology; Psychological and Brain Sciences
- Record Identifier
- 9984213276502771
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