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Active targeting schemes for nanoparticle systems in cancer therapeutics
Journal article   Open access   Peer reviewed

Active targeting schemes for nanoparticle systems in cancer therapeutics

James D. Byrne, Tania Betancourt and Lisa Brannon-Peppas
Advanced drug delivery reviews, Vol.60(15), pp.1615-1626
12/14/2008
DOI: 10.1016/j.addr.2008.08.005
PMID: 18840489
url
https://doi.org/10.1016/j.addr.2008.08.005View
Published (Version of record) Open Access

Abstract

The objective of this review is to outline current major cancer targets for nanoparticle systems and give insight into the direction of the field. The major targeting strategies that have been used for the delivery of therapeutic or imaging agents to cancer have been broken into three sections. These sections are angiogenesis-associated targeting, targeting to uncontrolled cell proliferation markers, and tumor cell targeting. The targeting schemes explored for many of the reported nanoparticle systems suggest the great potential of targeted delivery to revolutionize cancer treatment. (c) 2008 Elsevier B.V. All rights reserved.
Life Sciences & Biomedicine Pharmacology & Pharmacy Science & Technology

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