Journal article
Acute Histoplasmosis Choroiditis in 2 Immunocompetent Brothers
Archives of ophthalmology (1960), Vol.115(11), pp.1470-1472
11/01/1997
DOI: 10.1001/archopht.1997.01100160640023
PMID: 9366685
Abstract
Ocular infection with the fungus Histoplasma capsulatum may manifest in 2 ways. The first is an acute granulomatous uveitis or panophthalmitis that occurs in immunocompromised hosts. The second manifestation of ocular involvement by H capsulatum, seen in immunocompetent hosts, is the presumed ocular histoplasmosis syndrome (POHS). The syndrome is defined by peripheral atrophic scars, peripapillary atrophy, and choroidal neovascularization in the posterior pole (the "histoplasmosis triad"). It is still debated whether H capsulatum organisms have ever been definitively identified within these scars,1 and decades may elapse between the initial infection and the development of choroidal neovascularization.2 In addition, choroidal scars similar to those associated with POHS may be observed in other disorders. Although substantial epidemiological evidence exists that that there is a causal relationship between POHS and H capsulatum,3 the etiology of POHS remains unproven.Acute choroidal infection in immunocompetent patients rarely, if ever, comes to the
Details
- Title: Subtitle
- Acute Histoplasmosis Choroiditis in 2 Immunocompetent Brothers
- Creators
- Bradley J KatzWilliam E ScottJames C Folk
- Resource Type
- Journal article
- Publication Details
- Archives of ophthalmology (1960), Vol.115(11), pp.1470-1472
- DOI
- 10.1001/archopht.1997.01100160640023
- PMID
- 9366685
- NLM abbreviation
- Arch Ophthalmol
- ISSN
- 0003-9950
- eISSN
- 1538-3601
- Publisher
- American Medical Association
- Language
- English
- Date published
- 11/01/1997
- Academic Unit
- Ophthalmology and Visual Sciences
- Record Identifier
- 9983980291702771
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