Acute articular fracture severity and chronic cartilage stress challenge as quantitative risk factors for post-traumatic osteoarthritis: illustrative cases

K Z Masrouha; D D Anderson; T P Thomas; L L Kuhl; T D Brown; J L Marsh

$Acute articular fracture severity and chronic cartilage stress challenge as quantitative risk factors for post-traumatic osteoarthritis: illustrative cases$

Journal article

Open access

Peer reviewed

Acute articular fracture severity and chronic cartilage stress challenge as quantitative risk factors for post-traumatic osteoarthritis: illustrative cases

K Z Masrouha, D D Anderson, T P Thomas, L L Kuhl, T D Brown and J L Marsh

The Iowa orthopaedic journal, Vol.30, pp.47-54

2010

PMCID: PMC2958270

PMID: 21045971

Appears in Diamond Open Access

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958270/View

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Abstract

Novel biomechanical methods have been developed to objectively measure acute fracture severity (from inter-fragmentary surface area) and chronic contact stress challenge (from patient-specific finite element analysis) in articular fractures. These new methods help clarify the pathomechanics of the development of post-traumatic osteoarthritis, and can contribute directly to the clinical care of patients. In this manuscript, the value of these two new measures is demonstrated in three illustrative tibial plafond fracture cases, in which both metrics are correlated with cartilage status and with patient outcomes at a minimum of two years after injury. These clinical cases demonstrate the utility of new biomechanical variables to advance clinical research and patient care, by providing a basis to predict outcome and select treatment.

Radiography

Prognosis

Follow-Up Studies

Humans

Risk Factors

Tibial Fractures - diagnostic imaging

Male

Trauma Severity Indices

Tibial Fractures - surgery

Biomechanical Phenomena

Osteoarthritis - epidemiology

Cartilage, Articular - physiopathology

Tibial Fractures - physiopathology

Fracture Fixation, Internal

Adult

Female

Details

Title: Subtitle: Acute articular fracture severity and chronic cartilage stress challenge as quantitative risk factors for post-traumatic osteoarthritis: illustrative cases
Creators: K Z Masrouha - Department of Orthopaedics and Rehabilitation, The University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA
D D Anderson - University of Iowa, Orthopedics and Rehabilitation
T P Thomas - University of Iowa, Counselor Education
L L Kuhl
T D Brown - University of Iowa, Orthopedics and Rehabilitation
J L Marsh - University of Iowa, Orthopedics and Rehabilitation
Resource Type: Journal article
Publication Details: The Iowa orthopaedic journal, Vol.30, pp.47-54
Publisher: Dept. of Orthopaedics, The University of Iowa; United States
PMID: 21045971
PMCID: PMC2958270
ISSN: 1541-5457
eISSN: 1555-1377
Grant note: AR46601 / NIAMS NIH HHS P50 AR055533 / NIAMS NIH HHS P50 AR048939 / NIAMS NIH HHS R24 AR046601 / NIAMS NIH HHS AR48939 / NIAMS NIH HHS AR55533 / NIAMS NIH HHS R01 AR046601 / NIAMS NIH HHS
Language: English
Date published: 2010
Academic Unit: Roy J. Carver Department of Biomedical Engineering; Orthopedics and Rehabilitation; Industrial and Systems Engineering
Record Identifier: 9984051499902771

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