Journal article
Acute disseminated encephalomyelitis in a COVID-19 pediatric patient
Neuroradiology, Vol.63(1), pp.141-145
01/01/2021
DOI: 10.1007/s00234-020-02571-0
PMCID: PMC7527786
PMID: 33001220
Abstract
The authors present a case of acute disseminated encephalomyelitis in a COVID-19 pediatric patient with positive SARS-CoV2 markers from a nasopharyngeal swab. A previously healthy 12-year-old-girl presented with a skin rash, headache, and fever. Five days after that, she had an acute, progressive, bilateral, and symmetrical motor weakness. She evolved to respiratory failure. Magnetic resonance imaging (MRI) of the brain and cervical spine showed extensive bilateral and symmetric restricted diffusion involving the subcortical and deep white matter, a focal hyperintense T2/FLAIR lesion in the splenium of the corpus callosum with restricted diffusion, and extensive cervical myelopathy involving both white and gray matter. Follow-up examinations of the brain and spine were performed 30 days after the first MRI examination. The images of the brain demonstrated mild dilatation of the lateral ventricles and widespread widening of the cerebral sulci, complete resolution of the extensive white matter restricted diffusion, and complete resolution of the restricted diffusion in the lesion of the splenium of the corpus callosum, leaving behind a small gliotic focus. The follow-up examination of the spine demonstrated nearly complete resolution of the extensive signal changes in the spinal cord, leaving behind scattered signal changes in keeping with gliosis. She evolved with partial clinical and neurological improvement and was subsequently discharged.
Details
- Title: Subtitle
- Acute disseminated encephalomyelitis in a COVID-19 pediatric patient
- Creators
- Adelia Maria de Miranda Henriques-Souza - Hospital da RestauraçãoAna Claudia Marques Gouveia de Melo - Hospital da RestauraçãoBianca de Aguiar Coelho Silva Madeiro - Hospital Universitário Oswaldo CruzLeonardo Furtado Freitas - Beneficência Portuguesa de São PauloPedro Augusto Sampaio Rocha-Filho - Univ Pernambuco UPE, Hosp Univ Oswaldo Cruz, Recife, PE, BrazilFabricio Guimaraes Goncalves - Children's Hospital of Philadelphia
- Resource Type
- Journal article
- Publication Details
- Neuroradiology, Vol.63(1), pp.141-145
- Publisher
- Springer Nature
- DOI
- 10.1007/s00234-020-02571-0
- PMID
- 33001220
- PMCID
- PMC7527786
- ISSN
- 0028-3940
- eISSN
- 1432-1920
- Number of pages
- 5
- Language
- English
- Date published
- 01/01/2021
- Academic Unit
- Radiology
- Record Identifier
- 9984697728402771
Metrics
12 Record Views