Journal article
Acute effects of marijuana on cognition: Relationships to chronic effects and smoking techniques
Pharmacology, biochemistry and behavior, Vol.43(3), pp.907-917
1992
DOI: 10.1016/0091-3057(92)90424-E
PMID: 1448485
Abstract
A double-blind, placebo-controlled st study assessed acute effects on human cognition of marijuana smoking involving long or short durations of inhalation and breath holding. During eight test sessions, 48 adult, male volunteers completed standardized, pencil-and-paper tests of educational development and ability, as well as computerized tests of learning, associative processes, abstraction, and psychomotor performance. Marijuana impaired all capabilities except abstraction and vocabulary. These impairments were more pervasive than those associated with heavy, chronic marijuana use in a previous study involving the same tests, but showed some similarities. Marijuana altered associative processes, encouraging more uncommon associations. Marijuana-induced impairment in learning pairs of words was influenced by associative relationships between the words. There were a few hints that prolonged breath holding increased marijuana's effects under some test conditions, but in general it did not. Prolonged breath holding itself affected performance in four tests, regardless of whether subjects smoked marijuana or placebo. Whether physiological or psychological factors (e.g., exposure to carbon monoxide in smoke or subjects' expectations) produced these effects could not be determined.
Details
- Title: Subtitle
- Acute effects of marijuana on cognition: Relationships to chronic effects and smoking techniques
- Creators
- Robert I Block - Department of Anesthesia, University of Iowa, Iowa City, IA 52242, USARoxanna Farinpour - Department of Psychology, University of Health Sciences/The Chicago Medical School, North Chicago, IL 60064, USAKathleen Braverman - Mercy Hospital, Iowa City, IA 52245, USA
- Resource Type
- Journal article
- Publication Details
- Pharmacology, biochemistry and behavior, Vol.43(3), pp.907-917
- Publisher
- Elsevier Inc
- DOI
- 10.1016/0091-3057(92)90424-E
- PMID
- 1448485
- ISSN
- 0091-3057
- eISSN
- 1873-5177
- Language
- English
- Date published
- 1992
- Academic Unit
- Iowa Neuroscience Institute; Anesthesia
- Record Identifier
- 9984006326502771
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