Journal article
Acute myocardial infarctions, strokes and influenza: seasonal and pandemic effects
Epidemiology and infection, Vol.141(4), pp.735-744
04/2013
DOI: 10.1017/S0950268812002890
PMCID: PMC3733340
PMID: 23286343
Abstract
The incidence of myocardial infarctions and influenza follow similar seasonal patterns. To determine if acute myocardial infarctions (AMIs) and ischaemic strokes are associated with influenza activity, we built time-series models using data from the Nationwide Inpatient Sample. In these models, we used influenza activity to predict the incidence of AMI and ischaemic stroke. We fitted national models as well as models based on four geographical regions and five age groups. Across all models, we found consistent significant associations between AMIs and influenza activity, but not between ischaemic strokes and influenza. Associations between influenza and AMI increased with age, were greatest in those aged >80 years, and were present in all geographical regions. In addition, the natural experiment provided by the second wave of the influenza pandemic in 2009 provided further evidence of the relationship between influenza and AMI, because both series peaked in the same non-winter month.
Details
- Title: Subtitle
- Acute myocardial infarctions, strokes and influenza: seasonal and pandemic effects
- Creators
- E D Foster - 1Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, IA, USAJ E Cavanaugh - 1Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, IA, USAW G Haynes - 2General Clinical Research Center, Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA, USAM Yang - 1Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, IA, USAA K Gerke - 3Division of Pulmonary and Critical Care, Department of Internal Medicine, University of Iowa, Iowa City, IA, USAF Tang - 1Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, IA, USAP M Polgreen - 4Division of Infectious Diseases, Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA, USA
- Resource Type
- Journal article
- Publication Details
- Epidemiology and infection, Vol.141(4), pp.735-744
- DOI
- 10.1017/S0950268812002890
- PMID
- 23286343
- PMCID
- PMC3733340
- NLM abbreviation
- Epidemiol Infect
- ISSN
- 0950-2688
- eISSN
- 1469-4409
- Publisher
- Cambridge University Press; Cambridge, UK
- Number of pages
- 10
- Language
- English
- Date published
- 04/2013
- Academic Unit
- Statistics and Actuarial Science; Epidemiology; Biostatistics; College of Public Health; Injury Prevention Research Center; Internal Medicine
- Record Identifier
- 9983985716302771
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