Acute neuropsychological functioning following cardiosurgical interventions associated with the production of intraoperative cerebral microemboli

Jeffrey N Browndyke; David J Moser; Ronald A Cohen; Daniel J O'Brien; James J Algina; William G Haynes; Edward D Staples; James Alexander; Laurie K Davies; Russell M Bauer

doi:10.1076/clin.16.4.463.13910

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Acute neuropsychological functioning following cardiosurgical interventions associated with the production of intraoperative cerebral microemboli

Journal article

Peer reviewed

Acute neuropsychological functioning following cardiosurgical interventions associated with the production of intraoperative cerebral microemboli

Jeffrey N Browndyke, David J Moser, Ronald A Cohen, Daniel J O'Brien, James J Algina, William G Haynes, Edward D Staples, James Alexander, Laurie K Davies and Russell M Bauer

Clinical neuropsychologist, Vol.16(4), pp.463-471

12/2002

DOI: 10.1076/clin.16.4.463.13910

PMID: 12822055

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Abstract

Coronary artery bypass graft (CABG) and valve replacement (VR) surgical patients underwent neuropsychological assessment 1-2 days prior to surgery; 7-10 days postsurgery; and 1 month following hospital discharge. A group of matched healthy controls was tested at identical intervals. Cerebral microemboli in both middle cerebral arteries were quantified during surgery using Doppler sonography. Neuropsychological testing results revealed that the CABG and VR groups did not differ from one another at any assessment point. However, surgical patients performed more poorly than healthy controls across all assessments. Surgical patients, as a group, demonstrated a mild decline in attentional functioning and learning efficiency at the 7-10 day follow-up, but these difficulties essentially returned to baseline by the 1-month follow-up. Intraoperative microemboli counts were not significantly associated with postsurgical neuropsychological functioning in either the CABG or VR group.

Intraoperative Complications - psychology

Humans

Middle Aged

Male

Psychometrics

Case-Control Studies

Middle Cerebral Artery

Intracranial Embolism and Thrombosis - diagnostic imaging

Neuropsychological Tests

Cognition Disorders - diagnosis

Coronary Artery Bypass - adverse effects

Time Factors

Heart Valve Prosthesis Implantation - adverse effects

Intraoperative Complications - diagnostic imaging

Cognition Disorders - etiology

Intracranial Embolism and Thrombosis - etiology

Intraoperative Complications - etiology

Ultrasonography

Female

Task Performance and Analysis

Details

Title: Subtitle: Acute neuropsychological functioning following cardiosurgical interventions associated with the production of intraoperative cerebral microemboli
Creators: Jeffrey N Browndyke - Department of Psychiatry and Human Behavior, Brown Medical School, The Miriam Hospital, RI 02903, USA. jeffrey_browndyke@brown.edu
David J Moser
Ronald A Cohen
Daniel J O'Brien
James J Algina
William G Haynes
Edward D Staples
James Alexander
Laurie K Davies
Russell M Bauer
Resource Type: Journal article
Publication Details: Clinical neuropsychologist, Vol.16(4), pp.463-471
DOI: 10.1076/clin.16.4.463.13910
PMID: 12822055
NLM abbreviation: Clin Neuropsychol
ISSN: 1385-4046
eISSN: 1744-4144
Publisher: Taylor & Francis; England
Language: English
Date published: 12/2002
Academic Unit: Psychiatry; Medicine Administration
Record Identifier: 9984003404802771

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