Journal article
Acute renal failure caused by renal infiltration by hematolymphoid malignancy
Annals of diagnostic pathology, Vol.10(4), pp.230-234
2006
DOI: 10.1016/j.anndiagpath.2005.09.015
PMID: 16844565
Abstract
Renal involvement by a malignant infiltrative process is often suspected in patients with bilaterally enlarged kidneys and concurrent malignancies. Acute renal failure (ARF) can rarely occur secondary to such an infiltrative process. We present 2 cases in which ARF is attributable to malignant hematolymphoid infiltration. The first case involves diffuse, bilateral involvement of the kidneys by non–Hodgkin's lymphoma. The patient's renal function improved dramatically after the initiation of chemotherapy, clearly linking the development of ARF to the malignant process. In the second case, infiltration of the kidneys by plasma cell leukemia resulted in dialysis dependence. To our knowledge, this represents the first reported case of ARF attributable to documented renal infiltration by plasma cell leukemia. A review of the potential causes of renal failure in hematolymphoid malignancy, focusing on the direct impact of the infiltrative process and on the spectrum of renal disease in plasma cell dyscrasia, is presented.
Details
- Title: Subtitle
- Acute renal failure caused by renal infiltration by hematolymphoid malignancy
- Creators
- Steven E Lommatzsch - Department of Internal Medicine, University of Virginia Health System, Charlottesville, VA 22908, USAAndrew M Bellizzi - Department of Pathology, University of Virginia Health System, Charlottesville, VA 22908, USAHelen P Cathro - Department of Pathology, University of Virginia Health System, Charlottesville, VA 22908, USAMitchell H Rosner - Department of Internal Medicine, University of Virginia Health System, Charlottesville, VA 22908, USA
- Resource Type
- Journal article
- Publication Details
- Annals of diagnostic pathology, Vol.10(4), pp.230-234
- Publisher
- Elsevier Inc
- DOI
- 10.1016/j.anndiagpath.2005.09.015
- PMID
- 16844565
- ISSN
- 1092-9134
- eISSN
- 1532-8198
- Language
- English
- Date published
- 2006
- Academic Unit
- Pathology
- Record Identifier
- 9984047759702771
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