Journal article
Acute renal failure requiring use of continuous renal replacement therapy methods in the coronary care unit of a cardiac center
Cor et vasa (English ed.), Vol.52(3), pp.121-126
03/01/2010
DOI: 10.33678/cor.2010.036
Abstract
Introduction: Acute renal failure (ARF) requiring the use of renal replacement therapy methods is associated with a fairly poor prognosis of the critically ill, high mortality rates, and occurs in approximately 1-6% surgical and cardiac surgical patients. The incidence and relevance of ARF requiring the use of continuous renal replacement therapy methods has not been well characterized to date.
Aim: To determine the incidence of ARF requiring the use of continuous renal replacement therapy methods in the general population of the critically ill in the coronary care unit of a cardiac center and to define the short-term mortality rates of these patients.
Methods: Retrospective-prospective follow-up of all consecutive patients with ARF requiring the use of a continuous renal replacement therapy method in the authors' center over a period of more than seven years.
Results: Our group of patients comprised a total of 122 patients, i.e., 2% of 6,185 hospitalized patients over the study period. The most frequent causes of ARF included acute myocardial infarction in 36 (29%) patients, heart failure without cardiogenic shock in 64 (52%), with cardiogenic shock in 29 (24%), cardiac arrest with cardiopulmonary resuscitation in 26 (21%); 11 (9%) patients had had recent cardiac surgery, and a serious degree of pulmonary hypertension was present in 16 (13%) patients. The intensive care unit mortality was 42%, the 30-day mortality rate was 52%. Univariate logistic regression analysis identified cardiogenic shock, mechanical ventilation, catecholamine support, and sepsis as predictors of short-term mortality.
Conclusion: Acute renal failure requiring the initiation of continuous renal replacement therapy developed in 2% of patients hospitalized in the coronary care unit of our heart center. These patients make up an at-risk subgroup with acceptable short-term mortality. Our experience confirms the need to manage ARF as a complication of a variety of acute heart conditions and the appropriateness of mastering the technique of continuous renal replacement therapy in intensive care units taking care of individuals with acute heart conditions.
Details
- Title: Subtitle
- Acute renal failure requiring use of continuous renal replacement therapy methods in the coronary care unit of a cardiac center
- Creators
- Jan BělohlávekVladimír DytrychTomáš KovárníkOndřej ŠmídAleš Linhart
- Resource Type
- Journal article
- Publication Details
- Cor et vasa (English ed.), Vol.52(3), pp.121-126
- DOI
- 10.33678/cor.2010.036
- ISSN
- 0010-8650
- eISSN
- 1803-7712
- Language
- English
- Date published
- 03/01/2010
- Academic Unit
- Electrical and Computer Engineering
- Record Identifier
- 9984627183002771
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