Acute trimethyltin limbic-cerebellar syndrome

R BESSER; G KRÄMER; R THÜMLER; J BOHL; L GUTMANN; H. C HOPF

doi:10.1212/WNL.37.6.945

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Acute trimethyltin limbic-cerebellar syndrome

Journal article

Peer reviewed

Acute trimethyltin limbic-cerebellar syndrome

R BESSER, G KRÄMER, R THÜMLER, J BOHL, L GUTMANN and H. C HOPF

Neurology, Vol.37(6), pp.945-950

1987

DOI: 10.1212/WNL.37.6.945

PMID: 3587645

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Abstract

An acute limbic-cerebellar syndrome was seen in six industrial workers who inhaled trimethyltin (TMT). Clinical features included hearing loss, disorientation, confabulation, amnesia, aggressiveness, hyperphagia, disturbed sexual behavior, complex partial and tonic-clonic seizures, nystagmus, ataxia, and mild sensory neuropathy. Severity paralleled maximal urinary organotin levels. One patient died and two remained seriously disabled.

Toxicology

Biological and medical sciences

Medical sciences

Chemical and industrial products toxicology. Toxic occupational diseases

Metals and various inorganic compounds

Details

Title: Subtitle: Acute trimethyltin limbic-cerebellar syndrome
Creators: R BESSER - Univ. Mainz, dep. neurology, Mainz 6500, Germany
G KRÄMER - Univ. Mainz, dep. neurology, Mainz 6500, Germany
R THÜMLER - Univ. Mainz, dep. neurology, Mainz 6500, Germany
J BOHL - Univ. Mainz, dep. neurology, Mainz 6500, Germany
L GUTMANN - Univ. Mainz, dep. neurology, Mainz 6500, Germany
H. C HOPF - Univ. Mainz, dep. neurology, Mainz 6500, Germany
Resource Type: Journal article
Publication Details: Neurology, Vol.37(6), pp.945-950
Publisher: Lippincott Williams & Wilkins; Hagerstown, MD
DOI: 10.1212/WNL.37.6.945
PMID: 3587645
ISSN: 0028-3878
eISSN: 1526-632X
Language: English
Date published: 1987
Academic Unit: Neurology
Record Identifier: 9984020503502771

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