Addendum to the International Consensus Statement on Testing and Reporting of Antineutrophil Cytoplasmic Antibodies: Quality Control Guidelines, Comments, and Recommendations for Testing in Other Autoimmune Diseases

Judy Savige; Wayne Dimech; Marvin Fritzler; James Goeken; E. Chris Hagen; J. Charles Jennette; Rob McEvoy; Charles Pusey; Wendy Pollock; Michelle Trevisin; Allan Wiik; Richard Wong; International Group for Consensus Statement on Testing and Reporting of Antineutrophil Cytoplasmic Antibodies (ANCA)

doi:10.1309/WAEPADW0K4LPUHFN

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Addendum to the International Consensus Statement on Testing and Reporting of Antineutrophil Cytoplasmic Antibodies: Quality Control Guidelines, Comments, and Recommendations for Testing in Other Autoimmune Diseases

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Addendum to the International Consensus Statement on Testing and Reporting of Antineutrophil Cytoplasmic Antibodies: Quality Control Guidelines, Comments, and Recommendations for Testing in Other Autoimmune Diseases

Judy Savige, Wayne Dimech, Marvin Fritzler, James Goeken, E. Chris Hagen, J. Charles Jennette, Rob McEvoy, Charles Pusey, Wendy Pollock, Michelle Trevisin, …

American journal of clinical pathology, Vol.120(3), pp.312-318

09/2003

DOI: 10.1309/WAEPADW0K4LPUHFN

PMID: 14502794

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Abstract

Antineutrophil cytoplasmic antibody (ANCA) tests are used to diagnose and monitor inflammatory activity in Wegener granulomatosis, microscopic polyangiitis and its renal-limited variant (pauciimmune crescentic glomerulonephritis), and Churg-Strauss syndrome. The International Consensus Statement on testing and reporting of ANCA states that ANCA are demonstrated most readily in these conditions by using a combination of indirect immunofluorescence (IIF) of normal peripheral blood neutrophils and enzyme-linked immunosorbent assays (ELISAs) that detect ANCA specific for proteinase 3 or myeloperoxidase. The group that produced the International Consensus Statement has developed guidelines for the corresponding quality control activities, examples of comments for various IIF patterns and ELISA results, and recommendations for ANCA testing when inflammatory bowel disease and other nonvasculitic ANCA-associated autoimmune diseases are suspected.

Details

Title: Subtitle: Addendum to the International Consensus Statement on Testing and Reporting of Antineutrophil Cytoplasmic Antibodies: Quality Control Guidelines, Comments, and Recommendations for Testing in Other Autoimmune Diseases
Creators: Judy Savige
Wayne Dimech
Marvin Fritzler
James Goeken
E. Chris Hagen
J. Charles Jennette
Rob McEvoy
Charles Pusey
Wendy Pollock
Michelle Trevisin
Allan Wiik
Richard Wong
International Group for Consensus Statement on Testing and Reporting of Antineutrophil Cytoplasmic Antibodies (ANCA)
Resource Type: Journal article
Publication Details: American journal of clinical pathology, Vol.120(3), pp.312-318
DOI: 10.1309/WAEPADW0K4LPUHFN
PMID: 14502794
NLM abbreviation: Am J Clin Pathol
ISSN: 0002-9173
eISSN: 1943-7722
Language: English
Date published: 09/2003
Academic Unit: Pathology
Record Identifier: 9984203946402771

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