Adenylate cyclase activity in the families of alcoholics is controlled by a single major gene

Eric J. Devor; C. R. Cloninger; P. L. Hoffman; B. Tabakoff

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Adenylate cyclase activity in the families of alcoholics is controlled by a single major gene

Journal article

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Adenylate cyclase activity in the families of alcoholics is controlled by a single major gene

Eric J. Devor, C. R. Cloninger, P. L. Hoffman and B. Tabakoff

Alcohol and Alcoholism, Vol.26(Suppl 1), pp.157-160

01/01/1991

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Abstract

The stimulated activity of platelet adenylate cyclase (AC) has been shown to be significantly lower among alcoholics compared with controls. In this report we demonstrate that stimulated platelet AC activity is under the control of a single major gene locus. Thus a sensitive biological indicator of alcoholism has been shown to be highly heritable.

Obstetrics and Gynecology

Details

Title: Subtitle: Adenylate cyclase activity in the families of alcoholics is controlled by a single major gene
Creators: Eric J. Devor - University of Iowa
C. R. Cloninger
P. L. Hoffman
B. Tabakoff
Resource Type: Journal article
Publication Details: Alcohol and Alcoholism, Vol.26(Suppl 1), pp.157-160
ISSN: 0735-0414
Language: English
Date published: 01/01/1991
Academic Unit: Obstetrics and Gynecology
Record Identifier: 9983557405602771

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