Journal article
Adhalin mRNA and cDNA sequence are normal in the cardiomyopathic hamster
FEBS letters, Vol.364(3), pp.245-249
1995
DOI: 10.1016/0014-5793(95)00395-P
PMID: 7758576
Abstract
Adhalin is deficient in two forms of human muscular dystrophy, one due to mutations in the adhalin gene and one linked to an unidentified gene on chromosome 13. Because adhalin is deficient in skeletal and cardiac muscles of BIO 14.6 hamsters, which experience both myopathy and cardiomyopathy, cDNA encoding adhalin from BIO 14.6 hamster skeletal muscle was cloned and sequenced. Adhalin mRNA was expressed at normal levels in BIO 14.6 hamster cardiac muscle, and no mutation in adhalin coding sequence was found, indicating that the inherited myopathy and cardiomyopathy of the BIO 14.6 hamster are most likely not due to mutations in the adhalin gene.
Details
- Title: Subtitle
- Adhalin mRNA and cDNA sequence are normal in the cardiomyopathic hamster
- Creators
- Steven L RoberdsKevin P Campbell
- Resource Type
- Journal article
- Publication Details
- FEBS letters, Vol.364(3), pp.245-249
- Publisher
- Elsevier B.V
- DOI
- 10.1016/0014-5793(95)00395-P
- PMID
- 7758576
- ISSN
- 0014-5793
- eISSN
- 1873-3468
- Language
- English
- Date published
- 1995
- Academic Unit
- Neurology; Molecular Physiology and Biophysics; Iowa Neuroscience Institute
- Record Identifier
- 9984068380802771
Metrics
33 Record Views