Journal article
Admission Temperature and Associated Mortality and Morbidity among Moderately and Extremely Preterm Infants
The Journal of pediatrics, Vol.192, pp.53-59.e2
01/2018
DOI: 10.1016/j.jpeds.2017.09.021
PMCID: PMC5808888
PMID: 29246358
Abstract
To evaluate the temperature distribution among moderately preterm (MPT, 29-33 weeks) and extremely preterm (EPT, <29 weeks) infants upon neonatal intensive care unit (NICU) admission in 2012-2013, the change in admission temperature distribution for EPT infants between 2002-2003 and 2012-2013, and associations between admission temperature and mortality and morbidity for both MPT and EPT infants.
Prospectively collected data from 18 centers in the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network were used to examine NICU admission temperature of inborn MPT and EPT infants. Associations between admission temperature and mortality and morbidity were determined by multivariable logistic regression. EPT infants from 2002-2003 and 2012-2013 were compared.
MPT and EPT cohorts consisted of 5818 and 3213 infants, respectively. The distribution of admission temperatures differed between the MPT vs EPT (P < .01), including the percentage <36.5°C (38.6% vs 40.9%), 36.5°C-37.5°C (57.3% vs 52.9%), and >37.5°C (4.2% vs 6.2%). For EPT infants in 2012-2013 compared with 2002-2003, the percentage of temperatures between 36.5°C and 37.5°C more than doubled and the percentage of temperatures >37.5°C more than tripled. Admission temperature was inversely associated with in-hospital mortality.
Low and high admission temperatures are more frequent among EPT than MPT infants. Compared with a decade earlier, fewer EPT infants experience low admission temperatures but more have elevated temperatures. In spite of a change in distribution of NICU admission temperature, an inverse association between temperature and mortality risk persists.
Details
- Title: Subtitle
- Admission Temperature and Associated Mortality and Morbidity among Moderately and Extremely Preterm Infants
- Creators
- Abbot R. Laptook - Brown UniversityEdward F. Bell - University of IowaSeetha Shankaran - Wayne State UniversityNansi S. Boghossian - University of South CarolinaMyra H. Wyckoff - The University of Texas Southwestern Medical CenterSarah Kandefer - Research Triangle Park FoundationMichele Walsh - Case Western Reserve UniversityShampa Saha - Research Triangle Park FoundationRosemary Higgins - Eunice Kennedy Shriver National Institute of Child Health and Human DevelopmentRichard A. Polin - Columbia UniversityMartin Keszler - Brown UniversityBetty R. Vohr - Brown UniversityAngelita M. Hensman - Brown UniversityElisa Vieira - Brown UniversityEmilee Little - Brown UniversityAvroy A. Fanaroff - Case Western Reserve UniversityAnna Marie Hibbs - Case Western Reserve UniversityNancy S. Newman - Case Western Reserve UniversityBonnie S. Siner - Case Western Reserve UniversityWilliam E. Truog - Children's Mercy HospitalEugenia K. Pallotto - Children's Mercy HospitalHoward W. Kilbride - Children's Mercy HospitalCheri Gauldin - Children's Mercy HospitalAnne Holmes - Children's Mercy HospitalKathy Johnson - Children's Mercy HospitalKurt Schibler - Cincinnati Children's Hospital Medical CenterSuhas G. Kallapur - Cincinnati Children's Hospital Medical CenterCathy Grisby - Cincinnati Children's Hospital Medical CenterBarbara Alexander - Cincinnati Children's Hospital Medical CenterEstelle E. Fischer - Cincinnati Children's Hospital Medical CenterLenora Jackson - Cincinnati Children's Hospital Medical CenterKristin Kirker - Cincinnati Children's Hospital Medical CenterJennifer Jennings - Cincinnati Children's Hospital Medical CenterSandra Wuertz - Cincinnati Children's Hospital Medical CenterGreg Muthig - Cincinnati Children's Hospital Medical CenterEdward F. Donovan - Cincinnati Children's Hospital Medical CenterJody Hessling - Cincinnati Children's Hospital Medical CenterMarcia Worley Mersmann - Cincinnati Children's Hospital Medical CenterHolly L. Mincey - Cincinnati Children's Hospital Medical CenterC. Michael Cotten - Duke UniversityRonald N. Goldberg - Duke UniversityJoanne Finkle - Duke UniversityKimberley A. Fisher - Duke UniversityKathy J. Auten - Duke UniversityMatthew M. Laughon - Duke UniversityCarl L. Bose - Duke UniversityJanice Bernhardt - Duke UniversityCindy Clark - Duke UniversityBarbara J. Stoll - Emory University Hospital MidtownDavid P. Carlton - Emory University Hospital MidtownEllen C. Hale - Emory University Hospital MidtownYvonne Loggins - Emory University Hospital MidtownDiane I. Bottcher - Emory University Hospital MidtownStephanie Wilson Archer - National Institutes of HealthLinda L. Wright - National Institutes of HealthElizabeth M. McClure - National Institutes of HealthBrenda B. Poindexter - Riley Hospital for ChildrenGregory M. Sokol - Riley Hospital for ChildrenDianne E. Herron - Riley Hospital for ChildrenJames A. Lemons - Riley Hospital for ChildrenDiana D. Appel - Riley Hospital for ChildrenLucy C. Miller - Riley Hospital for ChildrenPablo J. Sanchez - Nationwide Children's HospitalLeif D. Nelin - Nationwide Children's HospitalSudarshan R. Jadcherla - Nationwide Children's HospitalPatricia Luzader - Nationwide Children's HospitalNehal A. Parikh - Nationwide Children's HospitalMarliese Dion Nist - Nationwide Children's HospitalJennifer Fuller - Nationwide Children's HospitalJulie Gutentag - Nationwide Children's HospitalMarissa E. Jones - Nationwide Children's HospitalSarah McGregor - Nationwide Children's HospitalElizabeth Rodgers - Nationwide Children's HospitalJodi A. Ulloa - Nationwide Children's HospitalTara Wolfe - Nationwide Children's HospitalAbhik Das - Research Triangle Park FoundationDennis Wallace - Research Triangle Park FoundationW. Kenneth Poole - Research Triangle Park FoundationKristin M. Zaterka-Baxter - Research Triangle Park FoundationMargaret Crawford - Research Triangle Park FoundationJenna Gabrio - Research Triangle Park FoundationJeanette O'Donnell Auman - RTI InternationalCarolyn Petrie Huitema - RTI InternationalBetty K. Hastings - Research Triangle Park FoundationKrisa P. Van Meurs - Lucile Packard Children's HospitalDavid K. Stevenson - Lucile Packard Children's HospitalM. Bethany Ball - Lucile Packard Children's HospitalMelinda S. Proud - Lucile Packard Children's HospitalWaldemar A. Carlo - University of Alabama at BirminghamNamasivayam Ambalavanan - University of Alabama at BirminghamMonica V. Collins - University of Alabama at BirminghamShirley S. Cosby - University of Alabama at BirminghamUday Devaskar - University of California, Los AngelesMeena Garg - University of California, Los AngelesTeresa Chanlaw - University of California, Los AngelesRachel Geller - University of California, Los AngelesTarah T. Colaizy - University of IowaDan L. Ellsbury - University of IowaJane E. Brumbaugh - University of IowaKaren J. Johnson - University of IowaDonia B. Campbell - University of IowaJacky R. Walker - University of IowaKristi L. Watterberg - University of New MexicoRobin K. Ohls - University of New MexicoConra Backstrom Lacy - University of New MexicoSandra Sundquist Beauman - University of New MexicoCarol Hartenberger - University of New MexicoBarbara Schmidt - Hospital of the University of PennsylvaniaHaresh Kirpalani - Hospital of the University of PennsylvaniaNoah Cook - Hospital of the University of PennsylvaniaSara B. DeMauro - Hospital of the University of PennsylvaniaAasma S. Chaudhary - Hospital of the University of PennsylvaniaSoraya Abbasi - Hospital of the University of PennsylvaniaToni Mancini - Hospital of the University of PennsylvaniaDara Cucinotta - Hospital of the University of PennsylvaniaCarl T. D'Angio - University of Rochester Medical CenterRonnie Guillet - University of Rochester Medical CenterSatyan Lakshminrusimha - University of Rochester Medical CenterDale L. Phelps - University of Rochester Medical CenterAnn Marie Reynolds - University of Rochester Medical CenterJulianne Hunn - University of Rochester Medical CenterRosemary Jensen - University of Rochester Medical CenterHolly I.M. Wadkins - University of Rochester Medical CenterStephanie Guilford - University of Rochester Medical CenterAshley Williams - University of Rochester Medical CenterMichael Sacilowski - University of Rochester Medical CenterLinda Reubens - University of Rochester Medical CenterErica Burnell - University of Rochester Medical CenterMary Rowan - University of Rochester Medical CenterKaren Wynn - University of Rochester Medical CenterDeanna Maffett - University of Rochester Medical CenterLuc P. Brion - The University of Texas Southwestern Medical CenterDiana M. Vasil - The University of Texas Southwestern Medical CenterLijun Chen - The University of Texas Southwestern Medical CenterLizette E. Torres - The University of Texas Southwestern Medical CenterWalid A. Salhab - The University of Texas Southwestern Medical CenterSusie Madison - The University of Texas Southwestern Medical CenterGay Hensley - The University of Texas Southwestern Medical CenterNancy A. Miller - The University of Texas Southwestern Medical CenterAlicia Guzman - The University of Texas Southwestern Medical CenterKathleen A. Kennedy - The University of Texas Health Science Center at HoustonJon E. Tyson - The University of Texas Health Science Center at HoustonJulie Arldt-McAlister - The University of Texas Health Science Center at HoustonCarmen Garcia - The University of Texas Health Science Center at HoustonKaren Martin - The University of Texas Health Science Center at HoustonGeorgia E. McDavid - The University of Texas Health Science Center at HoustonSharon L. Wright - The University of Texas Health Science Center at HoustonEsther G. Akpa - The University of Texas Health Science Center at HoustonPatty A. Cluff - The University of Texas Health Science Center at HoustonAnna E. Lis - The University of Texas Health Science Center at HoustonClaudia I. Franco - The University of Texas Health Science Center at HoustonAthina Pappas - University of Michigan–Ann ArborJohn Barks - Wayne State UniversityRebecca Bara - University of Michigan–Ann ArborShelley Handel - University of Michigan–Ann ArborGeraldine Muran - University of Michigan–Ann ArborDiane F. White - University of Michigan–Ann ArborMary Christensen - University of Michigan–Ann ArborStephanie A. Wiggins - University of Michigan–Ann ArborGeneric and Moderate Preterm Subcommittees of the NICHD Neonatal Research Network
- Resource Type
- Journal article
- Publication Details
- The Journal of pediatrics, Vol.192, pp.53-59.e2
- Publisher
- Elsevier Inc
- DOI
- 10.1016/j.jpeds.2017.09.021
- PMID
- 29246358
- PMCID
- PMC5808888
- ISSN
- 0022-3476
- eISSN
- 1097-6833
- Grant note
- National Institutes of Health (http://dx.doi.org/10.13039/100000002) National Center for Advancing Translational Sciences (http://dx.doi.org/10.13039/100006108) M01 RR80 / National Institutes of Health U10 HD21364; U10 HD21373; U10 HD21385; U10 HD27851; U10 HD27853; U10 HD27856; U10 HD27880; U10 HD27904; U10 HD34216; U10 HD36790; U10 HD40492; U10 HD40689; U10 HD53089; U10 HD53109; U10 HD68244; U10 HD68263; U10 HD68270; U10 HD68278; U10 HD68284 / National Institute of Child Health and Human Development (http://dx.doi.org/10.13039/100000071) UL1 TR6; UL1 TR41; UL1 TR42; UL1 TR77; UL1 TR93; UL1 TR442; UL1 TR454; UL1 TR1117; UL1 TR1111 / National Center for Advancing Translational Sciences
- Language
- English
- Date published
- 01/2018
- Academic Unit
- Stead Family Department of Pediatrics; Neonatology
- Record Identifier
- 9984354154702771
Metrics
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