Journal article
Adolescent idiopathic scoliosis
Nature reviews. Disease primers, Vol.1(1), pp.15030-15030
09/24/2015
DOI: 10.1038/nrdp.2015.30
PMID: 27188385
Abstract
Adolescent idiopathic scoliosis (AIS) is the most common form of structural spinal deformities that have a radiological lateral Cobb angle - a measure of spinal curvature - of ≥10(°). AIS affects between 1% and 4% of adolescents in the early stages of puberty and is more common in young women than in young men. The condition occurs in otherwise healthy individuals and currently has no recognizable cause. In the past few decades, considerable progress has been made towards understanding the clinical patterns and the three-dimensional pathoanatomy of AIS. Advances in biomechanics and technology and their clinical application, supported by limited evidence-based research, have led to improvements in the safety and outcomes of surgical and non-surgical treatments. However, the definite aetiology and aetiopathogenetic mechanisms that underlie AIS are still unclear. Thus, at present, both the prevention of AIS and the treatment of its direct underlying cause are not possible.
Details
- Title: Subtitle
- Adolescent idiopathic scoliosis
- Creators
- Jack C Cheng - Chinese University of Hong KongRené M Castelein - Department of Orthopedic Surgery, University Medical Center Utrecht, Utrecht, The NetherlandsWinnie C Chu - Chinese University of Hong KongAina J Danielsson - Department of Orthopedics, Sahlgrenska University Hospital, Gothenburg, SwedenMatthew B Dobbs - Departments of Orthopaedic Surgery Neurology and Pediatrics, Washington University School of Medicine, Saint Louis, Missouri, USATheodoros B Grivas - Trauma and Orthopaedic Department, Tzaneio General Hospital of Piraeus, Athens, GreeceChristina A Gurnett - Washington University in St. LouisKeith D Luk - Department of Orthopaedics and Traumatology, The University of Hong Kong, Hong KongAlain Moreau - Université de MontréalPeter O Newton - Rady Children's Hospital, San Diego, California, USAIan A Stokes - University of VermontStuart L Weinstein - Department of Orthopedic Surgery, University of Iowa Hospital and Clinics, Iowa City, Iowa, USAR Geoffrey Burwell - Nottingham University Hospitals NHS Trust
- Resource Type
- Journal article
- Publication Details
- Nature reviews. Disease primers, Vol.1(1), pp.15030-15030
- Publisher
- England
- DOI
- 10.1038/nrdp.2015.30
- PMID
- 27188385
- ISSN
- 2056-676X
- eISSN
- 2056-676X
- Language
- English
- Date published
- 09/24/2015
- Academic Unit
- Stead Family Department of Pediatrics; Orthopedics and Rehabilitation
- Record Identifier
- 9984040599602771
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