Journal article
Adsorption of Pluronic F-127 on Surfaces with Different Hydrophobicities Probed by Quartz Crystal Microbalance with Dissipation
Langmuir, Vol.25(11), pp.6245-6249
06/02/2009
DOI: 10.1021/la9001169
PMID: 19374344
Abstract
Triblock copolymers of polyethylene oxide (PEO) and polypropylene oxide (PPO), that is, PEO n-PPO m-PEO n, better known as Pluronic can adsorb to surfaces in either a pancake or a brushlike configuration. The brushlike configuration is advantageous in numerous applications, since it constitutes a surface repellent to proteins and microorganisms. The conformation of the adsorbed Pluronic layer depends on the hydrophobicity of the substratum surface, but the hydrophobicity threshold above which a brushlike conformation is adopted is unknown. Therefore, the aim of this study is to investigate Pluronic F-127 adsorption on surfaces with different hydrophobicities using a quartz crystal microbalance with dissipation. Adsorption in a brushlike conformation occurred on surfaces with a water contact angle above 80°, as inferred from the thickness, viscosity, and elasticity of the adsorbed layer. The concentration of Pluronic F-127 in solution affected only the kinetics of adsorption and not the final layer thickness or conformation of adsorbed Pluronic molecules. © 2009 American Chemical Society.
Details
- Title: Subtitle
- Adsorption of Pluronic F-127 on Surfaces with Different Hydrophobicities Probed by Quartz Crystal Microbalance with Dissipation
- Creators
- M Reza Nejadnik - University Medical Center GroningenAdam L. J Olsson - University Medical Center GroningenPrashant K Sharma - University Medical Center GroningenHenny C VAN DER MEI - University Medical Center GroningenWillem Norde - University Medical Center GroningenHenk J Busscher - University Medical Center Groningen
- Resource Type
- Journal article
- Publication Details
- Langmuir, Vol.25(11), pp.6245-6249
- Publisher
- American Chemical Society
- DOI
- 10.1021/la9001169
- PMID
- 19374344
- ISSN
- 0743-7463
- eISSN
- 1520-5827
- Language
- English
- Date published
- 06/02/2009
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Pharmaceutical Sciences and Experimental Therapeutics
- Record Identifier
- 9984420940702771
Metrics
15 Record Views